Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16663 Withaferin-a GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 69 GABPB1; PIAS2; EGR1; ATF3; JUN; NFIC; CREB3L2; DDIT3; SREBF1; ZNF410; FOXC1; VGLL1; PEG3; ZNF143; SIX2; ZBTB32; MAX; ETV5; NR4A2; TBX19; WWTR1; EN1; NR0B1; MED21; EZH2; SERTAD2; BANP; AR; EYA2; JUNB; ZMIZ1; SOX10; PITX1; MEIS2; PDLIM1; MEIS1; CBX4; TOX; TULP3; FOXF2; ZNF516; IRF4; MAFF; FOXG1; TRIM24; TCF21; ZNF331; NR2F1; MLXIP; HTATIP2; ZNF232; CREM; HES1; MSX1; SSBP2; ZNF423; SPEN; PIR; PAX6; HOXB2; HHEX; ID3; HOXB6; RORA; HOXB7; TWIST1; HOXD1; KDM5D; ZNF91
Down-regulation 57 MYC; NFKBIA; FUBP1; SP3; TXNIP; ADRB2; HMGA2; CHD4; ZNF146; TAF1D; STAT6; ZNF160; ZNF22; NFIL3; ZNF180; ELK3; NKX2-1; ETS2; E2F2; ZNF721; HMGB2; MYBL1; SOX4; ZNF281; FOXO1; SOX9; BRD2; TBL1XR1; PCGF2; RBL2; ZNF12; PA2G4; ARL2BP; PSIP1; ID1; HOXA10; ZSCAN31; KLF5; AFF1; TGFB1; MYRF; ZNF302; JARID2; RFX5; NFATC1; ING3; ID4; TCF7; CD3D; IFI16; BCL11B; THAP11; BASP1; HOXC6; PAX8; ID2; IKZF1