Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16662	Withaferin-a	GSE70138	MCF10A	Human	3h	10uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	97	EGR1; NR4A1; JUN; RBPMS; FOSB; NR4A2; ATF3; FOS; HLTF; FOXL2; TAF9; ING1; MYCN; GABPB1; USP16; TBPL1; DDIT3; CCDC59; AGO2; CREB3L2; BCLAF1; MEF2C; HSF2; POLR3F; RUNX3; CBX5; NCOR1; NKX3-1; HDAC5; NR1H2; CNOT6; NKX2-2; SSBP2; JUNB; ST18; MLXIP; VGLL1; WNT4; KDM5D; SMARCD3; PIR; NUP62; RBBP5; ARID1A; INSM1; SOX10; EYA2; KDM5A; NPM1; MTF2; ILF2; ZNF165; SMARCA5; FOXN2; HSBP1; TFAM; TBP; ZMIZ1; TCF21; SIX2; ECD; ARID4B; EGR3; XBP1; ARID5B; MAZ; HMGN3; PAX5; ZNF331; HOXD3; MBD2; ZNF226; MAGED1; ERG; FLNA; CTBP2; YWHAB; ID3; SPIB; CD3D; TULP3; RORA; KLF11; MEIS1; CREM; IRF8; IRF6; TCF4; ABL1; ZKSCAN1; RFX5; WT1; ID2; POU2AF1; BASP1; NR1D2; PEG3
Down-regulation	61	MYC; RARA; HMGA1; ELK3; TEAD4; ASH2L; TSC22D1; MYBL1; SATB2; GTF2I; LOXL2; KLF3; TCF3; ADRB2; HEY1; NFKBIA; BHLHE40; IRF9; YAP1; POU4F1; SOHLH2; PSMC3; NKX2-1; CRYM; TGIF1; NR2F6; RARG; GTF3A; SOX11; JUND; SMAD1; STAT3; ID1; PRRX1; FOXG1; GRHL2; SOX9; SIAH2; ATF5; ID4; TFAP2C; KLF5; PAX6; TLE1; TXNIP; ZNF512B; MYRF; ESR1; HOXA10; AHR; SCAND1; ARNTL2; HOXB6; ERBB4; BAZ1A; HIRA; HLF; MECOM; ZBTB18; TBX2; HOXB2