Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16661	Mitoxantrone	GSE70138	MCF10A	Human	3h	0.04uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	66	GATA2; CTR9; HEY1; RCOR1; BAZ1B; KAT6B; REPIN1; SMARCD2; NR4A1; ETV5; TSC22D1; BRD7; CNOT1; MED1; THAP11; PIR; MTF2; PCGF2; FOXG1; ISL1; GABPB1; DDX5; SOX9; ARID4B; FOSB; KDM5A; NFAT5; PITX1; CBFB; CALR; MITF; CREG1; BCL6; TRIM24; BAZ1A; ZNF160; SMARCC1; AES; HOXC6; NANOG; ZNF512B; CARM1; TBL1X; JUND; MXD1; PA2G4; ESR1; TAL1; MBD2; TLE4; KLF6; XBP1; TRIP6; MTA1; ASCL1; ZFP36L1; TRIM22; MNDA; MAF; INSM1; ID4; WT1; HMG20B; TBX3; TRIB3; KLF2
Down-regulation	87	PMS1; ZNF22; ELK3; SIX2; KLF10; TOX; CREB1; MED17; CERS6; IRF1; ZNF131; RYBP; ZFP36L2; BTG1; CNBP; VPS72; TGIF1; BBX; RAD21; CUX2; CDK9; ZIC1; MECP2; DDIT3; BHLHE40; PBX3; RXRA; FOXD1; ZBTB16; SMAD1; FOXC1; CTBP2; SERTAD2; SSBP2; MEOX2; CEBPD; FOXN3; SMAD2; TLE1; ZHX2; ING2; TBX21; BACH2; ZNF589; SUMO1; NLK; TCF7L1; SUPT3H; DMTF1; DNMT3B; ZNF232; KLF9; HHEX; SIAH2; SMAD7; PSIP1; ZNF329; NRBF2; MYB; PDLIM1; PTRF; PAX6; ZNF91; ZSCAN18; SCAND1; SPEN; CARHSP1; INSR; NEUROD1; ERBB2; SOX11; FOXF2; HIRA; NRIP1; HOXB6; ZNF423; HOXB7; PAX5; REL; DBP; ZNF43; SATB1; ZNF652; PEG3; NCOA1; HOXD1; TOX3