Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16656	Mitoxantrone	GSE70138	MCF10A	Human	3h	10uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	116	ZNF586; HMGA1; RBPMS; HIPK3; ZNF580; HEY1; ZNF544; SAP130; CNOT3; EYA1; NR1H3; MNAT1; GTF2I; ZNF444; RUVBL2; HSBP1; PATZ1; MEF2C; SREBF2; SPEN; ZNF419; TRIM28; SUPT6H; TLE4; HMG20A; ZNF587; HOXC10; CBX5; HAND1; ZNF175; MED16; E2F5; STAT2; ISL1; TRRAP; ELK3; RBBP4; ZNF536; NR2F1; TAF10; MAF; CHD4; WDR77; ZNF134; ZNF304; CITED2; TCF4; IRF7; TRIM22; HOXC4; TEAD1; TGFB1; IRF8; TSC22D1; EPAS1; FLI1; NFIB; HMGN3; CCNC; SP140; ZSCAN18; ZNF606; TAF9B; HHEX; FOXN3; TRAK1; ZNF415; HEY2; ID4; ZNF211; AHR; TFCP2; TRIP6; SALL2; SNAI1; ARID5B; PRRX1; ZNF532; ERBB4; ZEB1; TBL1XR1; SSBP2; ZMIZ1; ST18; ZNF467; LMCD1; ZBED2; NFKBIB; ZNF329; MAGED1; TOX; MYB; TFEC; CALR; PSIP1; PAX5; ZBTB18; HMGB3; ZNF665; HOXC6; BCL11A; TRPS1; MYRF; TWIST1; ZFPM2; ZNF551; ARID4B; MTA1; STAT1; ESR1; ZNF264; ZNF423; JARID2; ID3; SOX17; TRIB3
Down-regulation	106	NFKBIA; JUNB; NFIL3; HMGA2; BTG1; MYC; FOSL1; IRX4; CHD1; LITAF; EZH2; MED17; VPS72; CCNT1; RYBP; ZFP36L2; CNOT2; EGR4; TCF21; TRIM33; ZNF410; NCOA4; MYBL1; ADRB2; FOXD1; FOXA1; BIRC2; ZNF281; KLF6; IKBKAP; YAP1; ZNF500; BANP; BATF3; ZBTB3; PIAS1; FOXF2; SNIP1; SIX2; TXNIP; BRD8; UBE2I; TAF1D; RORA; SHOX2; KAT6B; CEBPB; DLX2; FOSL2; KLF7; MTF2; KLF10; TSC22D2; CEBPZ; RRN3; ZNF12; ZBTB16; GATA2; CEBPG; ZNF573; MEOX2; ING3; HOXD11; YBX3; TOB1; ZNF165; ZIC1; CUX1; ZBTB20; BHLHE40; TRIM29; JUND; NKX3-1; FOXO3; INSR; TLE1; SMAD7; CEBPD; PURA; FHL2; PBX3; ERBB2; MLXIP; HOXB7; NR2F6; ECD; CREM; HOXA5; TFDP2; RUNX3; HOXA10; SATB2; HES1; SMAD3; FOXG1; MEIS1; ZNF148; KLF11; KLF4; RBPJ; TBX2; MSX1; FOXJ3; THAP11; MNDA; MAFB