Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16653 Brivanib GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 66 FOXL2; GLI2; FOXF2; HMBOX1; PAX6; GATAD2A; HEY1; PLAGL1; PSMC3; CITED2; BARX2; NHLH1; ATOH1; PAWR; EHF; FOXF1; ZHX2; CHD8; KLF13; KDM5C; CERS4; PRRX1; RBPMS; ZNF611; CREB3L2; WWTR1; TOX; TBX2; ZNF175; ZMIZ1; NCOA3; PBX1; NR0B1; TBX3; ZBTB20; DLX2; HOXB2; HHEX; ATF3; SOX10; TFAP2C; TRIM29; ZNF512B; TCF21; TULP3; TLE4; SPEN; TGFB1I1; NFATC3; TP63; TGFB1; TOX3; LOXL2; SMARCB1; KLF9; ZEB1; TRIM22; TCF7L2; ZIC1; HIRA; TRIB3; ZNF264; HOXB5; NR2F6; INSM1; ZNF91
Down-regulation 37 EGR3; TRIM32; ZNF22; NKX3-1; SIX1; NR2F2; SIX2; GTF3A; ZNF239; NRBF2; ZNF131; SMAD7; TLE1; LEF1; ZNF423; CEBPA; HMGB3; PCGF2; MTF2; ZNF32; MECOM; LMCD1; IRF7; ZNF189; SMAD6; CREG1; ZBTB18; JARID2; ID2; IKBKAP; HOXC6; ADRB2; THAP11; KLF2; BMI1; RFX5; MYB