Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16639 As-601245 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 474 BRCA1; ETV5; ETV1; HDAC6; ARID5A; PCBD1; CERS4; RHOA; KLF12; HABP4; PBXIP1; KAT7; FOXA2; BATF3; ZNF76; PITX2; NFIL3; PBX2; DMRT1; SIX2; FOXO4; HNF4A; ATF3; CBX7; ZNF384; NKX3-2; RARB; HDAC5; NAB1; ETV4; ZNF787; LHX1; MEOX1; DDX17; SUB1; RELB; HAND1; SALL1; ZNF506; NR1H3; ZNF432; ESR2; NR4A1; SOX30; EN1; TAF5; ARID3A; SSX1; MEIS1; MYRF; ZKSCAN8; MLXIPL; RBL1; CITED1; ZNF580; ZNF408; RXRB; PAX8; HAND2; SP140; ETV7; VSX1; IKZF2; EYA1; CRYM; MNX1; SIN3B; MYF6; HIPK2; ZNF460; PHF1; MED1; FOXB1; EHMT2; PKNOX2; APBB1; EBF2; MTA2; PCGF2; IRF9; ZNF711; RING1; FOXD2; PITX1; SMARCD1; HCFC2; NR1I3; ZNF672; BRDT; HNF1A; FEV; MDM4; MXD3; HIVEP3; NKX2-5; ZNF814; LZTS1; ZNF415; SOX10; LBX1; THRA; JUP; ZNF442; ZFP2; ZNF34; ZMYM2; CUX1; KAT2A; TEAD3; NAB2; MSX1; ZNF133; MDM2; JUND; PHF2; OLIG2; HOXB3; TBX4; CREB3L1; MYCN; SSX7; HMGA1; ALX1; ETV2; TFDP3; NACA2; ZNF835; SIX6; PHOX2B; WIZ; AR; RORC; CRX; NR6A1; KAT5; MZF1; ZBTB17; PSMC3IP; ZNF493; MAK; CD3D; ERF; ZNF507; BARX1; POU2F3; ZNF492; FOXC2; HES2; ZNF254; PRDM16; ESRRG; SOX11; ZNF391; PIAS3; ZNF480; ZNF287; HOXD9; ZNF331; ANKRD1; TBR1; SOX12; ZNF528; SIX3; RFXANK; ZBTB40; GLI1; SSX3; HR; ATF7; BRD4; ZNF175; FOXF1; TRIM24; PAX2; CALCOCO1; RFX2; FOSL2; LYL1; ERBB4; TFAP4; TULP4; ZNF292; TAF6; MAFK; TBL1X; SALL2; ZKSCAN3; ZFHX4; ZKSCAN5; EZH1; NPAS1; ZNF500; POU3F4; HOXB2; MYF5; TAF11; CIITA; AFF3; POU2F1; ZBTB44; ZNF675; HOXB13; SREBF2; TFEB; ZNF248; IRF7; ZSCAN2; ZBTB48; TCF7L1; POU6F1; TEF; ATF6B; WHSC1L1; DLX4; PPARA; CDX2; THRB; GATA1; ZNF654; ZNF446; ZNF639; AFF4; ZNF205; NRF1; KLF13; ZNF562; CAMTA2; IL16; MDFI; ZNF154; SNAI1; HMBOX1; ZNF225; ARID4B; TULP1; SOX9; PRRX2; PMF1; ONECUT1; ZBTB32; NFKBIB; ZNF768; PRDM1; HOXC11; RERE; ZNF132; POU1F1; ERBB2; WNT4; PRDM8; HBP1; SRF; MYNN; ALX3; IRF3; ZNF202; EYA3; NR1H2; RBPMS; ZNF337; HOXA6; MEF2D; ZNF710; RFX3; TOX4; SSBP3; ZFY; BARX2; ZNF324; GCM1; ZNF221; MAPK8IP1; UBP1; PIAS4; ZBTB18; GFI1B; ZNF813; LEF1; BCL3; PAX4; HDAC9; ZSCAN32; TAL1; ZNF671; FOXD1; MBD4; HLTF; SKI; TXNIP; ZHX3; ZNF423; SAP18; TBX19; POLR3F; TAF10; SAFB2; TFEC; TP53; FOXJ2; SOHLH2; MAML3; MAX; PAX1; SOX5; ZNF552; MEOX2; KDM4C; ING4; NLK; KAT2B; SHOX; FHL5; EMX1; PHF8; RNF141; NEUROD6; LOXL2; BHLHE40; MEF2A; NEUROD1; HINFP; HOXA4; POU3F2; NFIX; HIVEP2; ABL1; HSF2; ZNF444; TULP2; PTTG1; FLI1; ADRB2; ELF3; PAX6; ZNF557; JARID2; ZNF556; CIR1; MNT; ZSCAN16; ZNF701; HNF4G; SOX17; EN2; MAFF; PDLIM1; NEUROG1; EYA2; PPARD; TBX1; KLF1; HIC2; CDIP1; NR2E1; SRY; GLI2; TLE4; NRL; PBX1; ZNF141; AES; ZNF606; CHD2; CBX4; SPI1; KDM5B; ZNF263; CREB3L2; FOXE1; ZNF214; STAT5B; GBX1; ZNF764; ATN1; ZIM2; TSC22D4; KLF15; HOXD3; MNDA; TRAK1; KDM2A; WT1; ZBTB43; SFMBT1; HOXC4; NHLH2; TCEB2; ARRB1; CREB5; TOPORS; NR4A3; ZEB1; NHLH1; PNRC1; SMAD7; ZNF419; USP21; SIAH2; RLF; SSBP2; TGFB1I1; ZBTB20; VGLL4; ARNT; CREM; GFI1; MEN1; BBX; DLX5; NPAS2; ARID5B; NKX2-2; NCOA2; E2F2; TCF7; SMARCA2; MED24; NEDD8; LPIN2; ZNF14; HEY1; KLF7; HOXA2; ASCL1; DMTF1; TFAP2C; CRY1; HLF; TBX3; EGR3; CALR; ADNP2; ATF6; ZNF44; PSIP1; RUNX3; ZNF467; MYT1L; ST18; IRF8; NR2F6; NR4A2; INSR; EHF; TLE2; MYC; MTA1; NCOA1; CHD7; ZIC1; PSPC1; HLX; MECOM; RFX5; STAT1; KLF5; HOXC10; NFATC3; KDM5D; PGR; SMARCA1; CARM1; ZSCAN18; HMG20B; ZNF85; TLE1; DBP; CRK; HOXA5; TOX3; HOXB6; MYB; HOXD1; TRIB3
Down-regulation 157 FOS; TFDP1; UBE2B; RNF4; CTCF; ATF5; TOB1; PMS1; STAT6; AHR; PBX3; RUNX1; BIRC2; BCL10; NFYB; TDP2; ZFP36L2; BANP; TAF1A; CCNH; MED14; CEBPG; PQBP1; SMAD4; PBRM1; TSC22D3; TAF4; MNAT1; CNOT1; RBBP7; RNF138; TSG101; XBP1; PAXBP1; BRD8; RB1; CEBPZ; ELK3; VDR; ABT1; ZMYND11; GABPB1; DDIT3; PPRC1; COPS5; SFPQ; CITED2; C1QBP; EWSR1; AEBP1; TCF3; BPTF; PHF20; C1D; CREB1; CHD1; RNF14; UBE2I; USP22; ZNF195; PHIP; SMAD2; CBFB; CCNC; MED23; PRPF6; CUX2; NFIB; RBBP4; ZBTB1; CERS6; CBX3; SUZ12; ARL2BP; TFAM; PLAGL2; BTAF1; GTF3A; MBD2; ID1; KLF10; MAGED1; HIRA; CNBP; MAFG; TBPL1; ZFX; TGIF1; AGO2; MYBL2; ZNF232; KMT2B; TBP; ELF1; TERF1; THAP4; DACH1; NUP62; SMAD1; ZNF22; NR1D2; MED12; NR2C1; ELF4; SPEN; CTBP2; CTNNB1; TCERG1; SRCAP; NR2F2; ETS2; POU4F1; ILF2; SMARCA5; VEZF1; HIPK3; SCAND1; SMARCA4; HIPK1; NR1I2; TMF1; RNF6; SOX4; HSBP1; ZNF12; YWHAB; NR2F1; HNRNPD; DDX5; REL; MAFB; EGR2; NFKBIA; RBBP8; NRBF2; ZBTB16; NFKB2; MTDH; ZNF512B; PA2G4; KLF11; ENY2; ZNF217; CARHSP1; BHLHE41; STAT3; ZNF32; SUV39H1; HMGB3; ID2; BAZ1A; SNAI2; FOXJ3; THAP11; ZNF430; TRIM29; ZNF652