Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16638 As-601245 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 330 BRCA1; RHOA; MEOX2; GTF2IRD1; RELB; KLF12; PCGF2; FOXO4; TFAP4; ETV1; RARB; EGR1; SLC2A4RG; PITX2; PAX8; EYA1; NR3C1; CERS4; TXNIP; PMF1; ACTL6A; LZTS1; SIX3; IKZF2; HMBOX1; ZNF646; TBX4; EYA3; APBB1; HMGA1; JUND; MNX1; ETV4; LITAF; HMGXB3; NKRF; PPARA; ZKSCAN3; MED24; PBXIP1; SALL2; BCL3; HNF1A; ZNF444; SSBP2; KAT5; HOXB3; GLI1; PKNOX2; SREBF2; SIX6; MYOG; FOXN1; SMAD5; CRYM; FOXA2; HNF4A; CALR; ZNF212; HOXC11; SHOX; CREB3L1; ZNF76; AIP; ZFY; ETV7; BRD4; NEDD8; THRA; ERBB4; THRB; FOXF1; ZNF331; MEOX1; TOX4; ZNF580; PCBD1; ZNF480; FOXI1; MYF6; NOCT; MYRF; ZNF197; ZNF507; KAT7; CITED1; SIRT2; ZNF552; CALCOCO1; SPI1; GTF2I; ASH1L; ZMIZ2; ZFP2; ZNF286A; POU2F3; NEUROD6; HIPK2; ZNF460; TSC22D1; NFAT5; CAMTA1; ASCL3; ZNF589; MED20; CBL; ONECUT2; ZNF133; REPIN1; EHMT1; RING1; ELF3; HIVEP3; PRDM1; SMARCD1; TAF6; ZNF787; MTA2; PROP1; SRY; HOXB13; MSX1; HR; BHLHE40; KDM4C; SIX5; PEX14; BARX1; TRIM25; PPARD; SPIB; NR3C2; ZNF282; MDM4; MED1; TCF15; ZNF235; ZNF205; HABP4; NR0B2; EHMT2; KLF15; SMAD1; ZKSCAN8; TFEB; FOXH1; GON4L; MSC; TRIM32; ZNF223; SOX9; NR1H2; SKI; TCF7; ZNF493; RORC; TFCP2L1; MXD3; TP53; BRF2; SSBP3; ETV3; ZNF587; WIZ; MAK; ETV5; CHD4; ZNF506; ARID3B; TADA3; TEAD1; OLIG2; ZNF175; CHD8; PAX2; RFX2; ERCC2; E2F2; MED27; CRX; ONECUT1; PAWR; ZNF835; CREM; NR1I3; ATF7IP; ARID1A; ZNF239; PRDM14; HOXA3; MYT1; ZNF154; CHD2; SALL1; MYCN; LMO1; ALX1; ZSCAN32; ZNF135; SUPT6H; HDAC1; HDGF; ZNF432; NR4A1; TGFB1; ZNF345; HEY1; TP63; TBX19; MDM2; CUX1; ZNF143; LHX3; HDAC11; GLI3; ESRRG; EN2; AR; ZBTB32; CD3D; BRWD1; SND1; HNF1B; NFE2L3; ZNF358; BATF3; MZF1; IRF9; FOXN2; RXRA; IFNB1; BTG1; CDX2; ZNF415; CIITA; AES; TSHZ2; DLX5; GBX1; ZNF606; SNAI1; ZNF33B; ZBTB44; ZIM2; PITX1; ZNF671; ZNF711; ZNF253; HOXA11; NR6A1; MEIS2; ING4; ZFHX4; ZNF544; EMX2; SOX12; TLE4; ERBB2; IL16; GRHL2; ZNF813; ARID3A; KLF7; TGFB1I1; RARG; SOX13; HOXC10; HOXB5; SIX2; SMAD3; HOXB2; SOX10; SP2; WNT4; RORA; TBX5; MITF; TRIM24; HOXA2; ZIC1; HOXD3; FOXE1; ZNF3; ZBTB43; OSR2; NR5A2; NFATC3; SUMO1; IRF8; NKX2-1; PAX6; LOXL2; ZNF93; RBFOX2; CASZ1; PDLIM1; MTA1; TRIM16; HOXD1; TBL1X; SOX11; USF2; RBL2; RUNX3; HOXB6; NR2F6; ZNF85; TULP3; MNDA; DBP; JUP; GFI1; FOXF2; ZEB1; POU2AF1; HMG20B; CEBPA; RBPJ; PBX1; NR4A3; TOX3; ZNF394; TCF4; ZNF423; VPS72; ASCL1; HOXB7; STAT4; PEG3; TRIB3
Down-regulation 174 TFDP1; NFYB; NFIB; ELK3; CBX3; PQBP1; RNF4; CEBPB; HMGA2; TCEA1; ZMYM2; CHD1; TOB1; BCL10; CDC5L; ITGB3BP; RNF138; NR2C1; PMS1; XBP1; RNF6; ATF5; PPRC1; VDR; HTATIP2; CBFB; ZBTB16; FHL2; ERG; FUBP1; TRIM33; TBP; GABPB1; BTAF1; ZBED2; KLF10; USP22; RNF14; COPS5; TAF1A; ZBTB11; C1QBP; DDX5; CEBPG; ZFP36L2; TSC22D3; BRD7; AHR; PHIP; CTCF; RCOR1; ZBTB1; MBD2; SNW1; TBPL1; TSC22D2; HHEX; RBM39; IFI16; RCOR3; ERCC3; RUNX1; ADNP; COPS2; TGIF1; ARID4A; SPEN; NR2F2; CSDE1; DNAJC2; TRPS1; CUX2; CTR9; ING1; ZNF165; NRIP1; ZNF512B; DR1; TAF12; ZZZ3; ATF1; ENY2; ZFPM2; CTBP1; TAF7; BAZ1A; NUP62; NFKBIA; SCAND1; ZNF84; SP110; MTDH; BRD8; UBE2B; TRIM27; ZBTB20; ZNF302; RFC1; ZNF32; PUF60; ZNF24; MTF2; HSF2; CHD9; HIPK1; ELF1; SUZ12; FOSL1; BAZ1B; MYBL1; CARHSP1; RBBP4; NPM1; CITED2; PTRF; GCFC2; CEBPZ; BMI1; RREB1; TDRD3; SUPT3H; CCDC59; SOX4; CTBP2; SAP30; YWHAB; SMAD4; RYBP; TBL1XR1; TFAP2C; ZNF217; CCNC; AEBP1; SMARCA5; SFPQ; BHLHE41; ZNF721; FOXJ3; RRN3; ZNF12; CRY1; TCF7L2; ZNF652; DEK; FLNA; HMGB3; ZNF83; ZNF532; MEIS1; GATA6; ZNF426; PBX3; THAP11; FOXO3; MAFB; DNAJC1; CHD7; WT1; ID1; HMGN3; SNAI2; PSPC1; MYC; INSM1; LMCD1; SUV39H1; PHF20; MAF; CCNA2; ZNF267; HOXC6; TRIM29; ZNF430; BASP1