Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16637 Linsitinib GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 71 NR3C1; NR4A2; NUP62; KAT6A; BNC2; ZNF140; SOX13; IRF1; EMX2; PHIP; WNT4; BTG1; SOX2; ZFPM2; MED23; MITF; MEF2C; CITED2; TAF5L; TCF20; WT1; HMGXB4; SHOX2; FOXN3; IRF8; TCF4; ZMYM2; HIPK1; ZNF160; KLF6; ZNF304; ATF3; CTBP1; ZBTB20; ZEB1; NR4A1; KLF11; ZNF268; CSDC2; ZNF331; NR1H2; HOXB2; ZNF175; HBP1; ZNF12; MEIS1; OSR2; CUX1; E2F8; NR2F1; BASP1; ZBTB38; ZNF264; CRYM; PBX3; PEG3; IKBKAP; ETS2; SPEN; ARID4B; TRIM22; PSIP1; PIR; ESR1; MYRF; FOSB; HOXB5; SNAI2; BHLHE41; HOXD1; TRIB3
Down-regulation 57 RARA; ENO1; GTF2IRD1; BCL3; PHOX2B; PRMT2; SIX2; SOX9; YBX1; PDLIM1; LZTS1; TP53; SREBF1; SMARCE1; SIX3; SMAD7; GTF2I; NR2F6; CEBPB; HDAC1; DMTF1; CEBPG; KAT8; EYA1; REPIN1; NEDD8; ELF1; DLX2; NR1I2; CBFB; LITAF; SMARCA4; ZNF423; FOXC1; CTNNB1; SOX11; TBL1X; TAF10; ZFHX4; BIRC2; FOXG1; ENY2; PITX1; FLNA; MSX1; MTDH; ADRB2; SMAD3; SMAD6; ELF5; FOSL1; SMARCA1; LPIN2; IRX5; BCL11B; ID1; SATB1