Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16636	Linsitinib	GSE70138	MCF10A	Human	3h	0.12uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	BRD3; TSC22D3; NR2F1; ITGB3BP; EYA1; BPTF; TEAD1; DDX5; NR2F2; RAD21; RBPMS; PKNOX2; BRD8; SOX2; TLE4; NFE2L1; POU2AF1; ARID4B; HMGB2; SUB1; TCF21; SMAD1; ERBB2; PEG3; DEK; MED24; TBX2; ZIC1; FOXD1; MTDH; FOXF1; VEZF1; SMAD6; MBD2; SAP30; RAN; EHF; WT1; SALL1; PRKDC; MYRF; STAT1; PSIP1; ID3; TRIM22; ZFP36L1; KDM5D; ID4; TBX3; SNAI2; MEIS2; CCNA2; BASP1
Down-regulation	64	RUNX1; PSMC3; ZNF266; ZNF219; FOSL2; NR0B1; KLF4; NFE2; POLR3C; RNF14; ZIC3; BCL6; ATF3; OVOL2; DLX4; ZNF165; CREB3L1; SHOX2; CRYM; CREM; KLF10; NFATC4; HIC2; ZNF131; VPS72; TFEC; NR1H2; TAF1D; LIN28A; CBFA2T3; EGR2; NFE2L3; HTATIP2; ZBTB16; PRRX1; ZNF107; ZNF665; EYA2; TLE2; PAX6; PRDM2; SOX10; NEUROD1; ZNF14; TAF1; NFATC1; KLF11; ZNF44; ZSCAN18; TCF7L2; DACH1; ZNF43; REL; HOXC6; CARHSP1; ZNF264; ZNF91; ZNF430; ERBB4; MNDA; SOX17; MECOM; DBP; BCL11B