Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16635	Linsitinib	GSE70138	MCF10A	Human	3h	0.37uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	84	DAXX; KAT7; TSC22D3; ZMYM2; RUNX1; NCOA4; TFDP1; SP3; TRIM22; ELK4; HSF2; MED24; WWTR1; CDK7; GABPB1; ELK3; SP100; ING2; HLTF; MED23; PRKDC; CDK2; RNF138; ARID4B; TCEB2; CENPF; CREG1; HMGB2; ZFP36L2; SMAD2; CNOT6; ERBB2; PIR; SMARCC1; NKX3-1; CEBPZ; FOXO3; TLE4; TAL1; RUVBL2; WNT4; PTTG1; CTBP1; HIPK1; ATF1; SMAD4; TXNIP; ASH2L; TRIM16; SUB1; SFPQ; ZBTB18; HOXC6; CBFB; NKX2-1; TULP4; USP22; JUND; CITED1; RREB1; AFF1; TFAP2C; DEK; ECD; TCF21; NFKBIA; ASCL1; HOXA5; VEZF1; MBD2; TSC22D2; IFI16; TRIM29; GMNN; JARID2; KLF2; ZEB1; NRIP1; BHLHE41; CCNA2; KDM5D; HOXD1; BASP1; SNAI2
Down-regulation	134	ETS1; CCNH; ZBED1; ZNF562; CBX6; ZNF415; ZNF202; VPS72; BRD4; KMT2A; ZBED2; MLXIPL; BTG1; HINFP; MYCN; ZNF135; SOHLH2; RNF4; NR1H3; FOXG1; SRF; ERBB4; NFE2; SUPT3H; TRIB3; RXRA; DMTF1; NFATC4; TGFB1; SATB2; ZNF165; ATF5; PAX6; LIN28A; CDIP1; HIC2; CREB3L2; ZNF556; BHLHE40; EMX2; LOXL2; ZNF544; ZNF665; SIX1; ZNF467; ZNF573; AR; SPI1; JUN; MECP2; TSC22D1; L3MBTL1; ZNF141; ZNF131; HMBOX1; TOX3; PBX1; DDIT3; MEOX1; BATF; MYCL; ST18; RYBP; ZNF232; NR5A2; IRF4; SAP18; ZIC3; ZSCAN18; FOXA1; PDLIM1; SMAD1; ZNF22; NLK; CBFA2T3; XRCC6; TOX; ZNF7; BCL6; HDAC4; HMGB3; MYT1L; MEIS1; NR0B1; ATN1; NRBF2; ZNF91; ZNF83; ENO1; EGR2; NCOA1; ZBTB38; ISL1; SSBP2; ZNF148; PITX1; VDR; NKX2-2; TRPS1; ZNF44; ZNF426; TLE1; SPIB; REL; ZNF629; SPEN; THAP11; CCNC; TCF4; RBFOX2; TDRD3; TCF7L2; DACH1; PIAS1; ZNF652; TAF1; ZNF331; IRF8; ZNF329; FOXC1; RNF141; IKBKAP; ZNF85; HMGB1; MEIS2; HOXB6; IRX5; ZNF43; MEF2C; ID2; TWIST1; ZNF184; IKZF1; MAFB