Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16634	Linsitinib	GSE70138	MCF10A	Human	3h	1.11uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	65	TSC22D3; PFDN5; TADA3; RBBP7; ZBTB38; PPARGC1A; DDX5; RBBP4; MEOX2; JUNB; NCOA3; NCOA6; RBM39; MBD2; C1D; NCOA4; EYA1; YBX1; CTR9; YWHAB; UBP1; ITGB3BP; MED24; MYT1L; CBFB; FOXD1; SMAD2; NEDD8; COPS2; CBX5; UBE2I; NPM1; DR1; HOXA5; PUF60; NR3C2; TRIM28; EYA2; DEK; SUB1; MAZ; PAX5; NFKBIA; KLF10; MTDH; KAT6B; PSIP1; MTF2; EMX2; MED1; HOXC6; GMNN; KLF2; NR2F2; SMAD3; KDM5D; NR1D2; HMGB1; CREG1; CCNA2; KLF9; CALR; HOXC10; HOXB7; HMG20B
Down-regulation	172	SSX1; KAT2A; SOHLH2; PBX3; POLR3C; SP140L; SOX13; TFAP2C; SNAPC4; SHOX2; ZNF692; CDK9; ZNF202; MNX1; RARA; EHMT2; TCF7L1; SETDB1; JUN; GON4L; IRF9; MYBL1; TRPS1; BHLHE41; WT1; SIN3B; NFE2L3; TCEA2; PAX6; CBFA2T3; ZNF589; ARNT; BAZ2A; AEBP1; NCOA2; FUBP1; MEIS1; ZBTB16; ARRB1; BRD7; ZBTB48; ARID5A; VPS72; FOXI1; BAZ2B; DMTF1; SUZ12; CBFA2T2; TP73; BNC2; ZNF512B; YAP1; CBX2; MBD4; ZXDC; CERS4; HLX; HINFP; HIC2; ZFPM2; PRDM1; LMCD1; SOX5; RXRA; NKX2-1; ZNF211; MEIS2; CBX4; PRRX1; ILF2; TAF1C; HMBOX1; BATF; TCF7L2; ZNF224; FLI1; SALL2; CHD7; FOSL2; ZNF273; IRF8; TWIST1; ZNF611; NR1H2; TLE2; ING4; ZNF117; CHD9; KLF13; MAF; ZNF93; ZMIZ1; KLF4; WNT4; NR4A2; IRF4; CEBPB; DEAF1; HMGN3; HHEX; SOX2; TBX2; ZNF195; BCL6; ZNF671; ZNF12; ZNF227; ZSCAN9; CTBP1; RUNX1; SPDEF; FOXA2; MYRF; BRWD1; IL16; SSBP2; NR4A1; ZNF232; DLX2; PBX1; NFATC3; SOX11; TCF21; GRHL2; E2F2; ZNF652; HOXD3; ZEB2; NFATC4; TTF1; SUPT3H; ST18; TRIP6; TCF4; GLI2; EGR2; ZNF83; ELF5; KLF11; ZNF264; NR0B1; SMARCC2; ZNF134; ZEB1; ZNF551; TULP4; FOXE1; NR4A3; IFI16; ZKSCAN1; CARHSP1; FOXF2; SOX17; PDLIM1; IKZF1; ZSCAN18; MEF2C; FOSB; THAP11; ARNT2; TFDP2; LEF1; ZNF43; ZIC1; NCOA1; DACH1; MNDA; ID4; TLE1; ZNF91; ZNF430; MAFB