Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16633 Linsitinib GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 111 CEBPZ; ZNF205; BNC2; CUX2; SIX5; ZNF177; ZNF623; MDM2; TSC22D3; PBX3; SLC2A4RG; TCF7L1; RAX; NANOG; PNRC1; TEAD1; HOXA4; PEG3; MLLT10; ZNF268; POU5F1B; HMBOX1; MEIS2; ZNF219; SALL2; CREB3L2; CERS4; PBX1; XBP1; ZNF432; SOX2; HIF3A; HDAC5; NR2F1; BARX1; CBFA2T3; SMAD1; CEBPE; PRDM1; SOX18; KDM5C; ZNF117; PLAG1; ZMIZ1; ZNF500; ZHX2; ZSCAN9; TLE2; ZNF573; GLI2; L3MBTL1; PKNOX2; PRDM14; KMT2A; RBPMS; ZNF93; PEX14; TULP3; ZNF586; HLX; NR1H2; ARID1A; KLF7; ATN1; SMARCA1; TCF4; NFE2L3; MEOX1; PHIP; ZNF304; NFATC3; SOX11; NR5A2; NEUROD1; HHEX; ZNF544; PAX6; SPEN; CITED2; ATF6; PRDM2; HEY1; ZNF606; POU2AF1; NR2F6; ST18; ZNF232; NFATC4; ZNF217; IRF8; INSM1; ZFPM2; JUP; CREB1; ZNF423; NFKB2; ZIC1; ARID5B; ZEB1; ESR1; ZNF43; HOXA5; ERBB4; TFAP2A; ABL1; ZNF91; SOX17; DACH1; FOXF1; ZSCAN18; TRIB3
Down-regulation 45 NKX3-1; RBBP7; TFDP1; RNF14; HLTF; RNF4; RNF6; TBL1XR1; HSF2; BBX; ATF1; YBX1; BRD2; LEF1; NUP62; MED1; BIRC2; ZNF226; MYC; EGR3; MAGED1; SMARCA2; SOX9; KLF5; HOXC10; ZBTB18; TOB1; USP22; HMGN3; RFX5; BCL11B; MAF; FOSL1; KDM5D; IKBKAP; BAZ1A; HOXC6; CARHSP1; HOXA10; HOXB7; SATB1; GATA3; MAFB; LPIN2; BHLHE41