Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16631 Ruxolitinib GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 27 PPARG; VGLL4; BNC2; TBX2; LOXL2; PTRF; PITX1; ID3; ID1; JUP; KLF5; FOXG1; SPEN; HMGB3; POU2AF1; HES1; INSM1; NR2F6; SALL1; TWIST1; FOXF1; ZEB1; RBPJ; MEIS2; CREB1; TRIB3; ZNF91
Down-regulation 28 HDAC4; HSF2; SERTAD2; E2F2; GATA6; NCOA4; MEF2A; OSR2; NRBF2; ID2; ZBTB16; ERG; STAT3; ZEB2; LPIN2; LMCD1; SATB1; HOXC10; JARID2; HOXC6; MYB; KLF2; ZNF267; NCOA1; FOSB; RFX5; MAFB; IKZF1