Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16630 Ruxolitinib GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 44 TCFL5; BNC2; KLF6; PBX3; EN1; PEG3; TEAD1; CREB3L2; NFATC3; PTRF; TCF21; SIX2; BARX1; WT1; CERS4; EMX2; CRY1; KLF13; NR1H2; ZNF573; NKX2-2; GRHL2; FOXM1; CUX1; BCL11A; ID2; TGFB1I1; SPEN; FLNA; MEIS1; HOXD1; AEBP1; HLF; IKBKAP; STAT1; ZFPM2; FOXE1; CREB1; ASCL1; ID1; RBPJ; ZNF264; MYB; SNAI2
Down-regulation 34 TSG101; CEBPB; PFDN5; SSX1; NR2F6; EYA1; ELF1; TRIB3; ZNF266; ELF3; IRF5; EGR3; DMTF1; NRBF2; LPIN2; LMCD1; BACH1; HDAC9; BHLHE41; MNDA; ZBTB18; EGR2; ZNF267; FOSB; ZEB2; TBX2; GATA3; SATB1; STAT4; MAFB; NR1D2; ZNF430; ID4; IKZF1