Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16627 Ruxolitinib GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 45 ZMYM2; NR4A2; MEF2C; CREB3L2; KLF6; ZBED2; FOXL2; PCGF3; KDM5A; EN1; NFAT5; TRPS1; KDM5B; PAWR; WT1; TFAP2C; NFIB; IL16; BANP; ZNF721; PBX1; DLX2; SFPQ; MEIS1; TCF4; HOXD3; TDP2; CITED2; TSC22D2; ZNF331; FOXM1; TCF21; TULP4; VDR; RREB1; ELF5; NR2F2; SPEN; HOXD1; NR2F6; IRF6; AEBP1; ZFPM2; ZNF264; TRIB3
Down-regulation 40 ZBTB1; KAT7; ZNF580; TRIM16; TGIF1; POU4F1; NCOA4; HMGA1; DDX5; SOX9; NKX3-1; PIR; ID1; ID4; LEF1; ZNF22; HDAC1; THAP11; SMAD7; SMARCA4; PCGF2; MSX1; MYBL1; HDAC9; TLE1; ID2; TOB1; PSIP1; MYB; SMAD6; LPIN2; ADRB2; HOXC6; TXNIP; MTA1; TFDP2; TBX2; RFX5; KLF2; IKZF1