Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16626 Ruxolitinib GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 39 PQBP1; PITX2; HOXA7; HIPK3; EGR1; CDX2; ELF4; CDX1; KLF10; GATA6; CENPF; SPEN; ZFPM2; PITX1; SOX2; MAZ; NR4A2; ENO1; NR4A1; TAL1; DACH1; ATF3; HOXA5; CARM1; HMGB3; ABL1; ARID4B; NR4A3; PBX3; TSC22D2; PBX1; FOXF2; FOSB; BASP1; ZEB1; FOXF1; MECOM; TRIB3; ZFP36L1
Down-regulation 44 EED; FUBP1; PMS1; PIAS2; TGIF1; HSF2; EZH2; TBP; UIMC1; CRYM; DMTF1; BTAF1; ZMYM2; EZH1; ZNF107; BBX; LITAF; OSR2; CTNNB1; ADRB2; BACH2; LEF1; MYBL1; MYB; ZBTB25; TLE1; HOXC10; KAT6B; RORA; ELF5; SOX10; HDAC9; THAP11; HLF; HMGB1; BHLHE41; TXNIP; HOXC6; FOXC1; LPIN2; ID2; ZNF264; ESR1; ZNF652