Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16624	Alpelisib	GSE70138	MCF10A	Human	3h	0.12uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	WWTR1; TCFL5; ZNF589; PMS1; ZEB1; IRF3; ZBTB20; RBM39; ZMYND8; PAWR; ID3; SOX10; BCL3; EN1; CHD9; NR2F1; PRPF6; ZNF512B; SOX2; ID1; EHF; KLF10; ZNF593; ARID4B; SIX2; TFAP2C; PRRX1; VEZF1; AHR; BASP1; ZNF217; BLM; CUX1; SATB1; HHEX; ZNF232; KAT6B; SPEN; YWHAB; FOXG1; LITAF; ZNF532; ZNF131; TCF7L2; TRIM22; HTATIP2; HOXA5; HES1; RBBP8; ZSCAN18; PAX8; ZIC1; BMI1; NR2F6; TRIB3
Down-regulation	60	GTF2IRD1; POU4F1; BTG1; BRD4; CHD3; MYCL; DLX2; BRD2; PNRC1; HOXA1; SMARCD3; FLI1; MEOX2; COPS5; BAZ2A; FOXA1; ZNF467; SAP18; NR3C2; PCGF2; ZEB2; MAF; NKX2-2; ZNF226; BHLHE41; NKX3-1; HIRA; ISL1; KLF4; VDR; CRYM; GATA6; THAP11; NR0B1; INSR; CD3D; MYT1L; RLF; URI1; ST18; MSX1; GFI1; MNDA; DACH1; PEG3; ID2; ZNF148; ZNF136; BCL11B; HOXC6; LPIN2; KLF2; INSM1; NR1D2; MECOM; MXI1; RFX5; DBP; IKZF1; ID4