Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16623	Alpelisib	GSE70138	MCF10A	Human	3h	0.37uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	60	EED; ELK3; MEF2C; KDM2A; SREBF1; TRIP6; SMARCE1; RBBP4; TSC22D3; SMARCD2; SAFB2; MAX; PTTG1; ITGB3BP; COPS2; NFIB; REPIN1; CENPF; SOX10; MED24; WWTR1; UBE2I; DEK; TRIM16; BMI1; SAP30; NPM1; PIR; ZBTB18; TAF10; HNRNPD; TRIM28; KAT6B; PSIP1; CREG1; RFX5; ZNF589; PCGF2; HOXC6; SPEN; MBD2; MLXIP; ATF6; NR2F2; HOXA5; ABL1; ATF4; PAX5; MTA1; BASP1; TLE1; RBPJ; HDGF; MYB; HMGB1; DACH1; HMG20B; SCAND1; KDM5D; KLF2
Down-regulation	178	TCEA1; NFE2L2; CCNH; MED13; FOXL2; SCAI; ZNF257; ZNF273; ZMIZ1; ZNF254; WWP1; ETS1; RING1; OLIG2; BCOR; MED14; ZNF550; ZNF492; ZNF675; ZNF493; DLX2; ELF3; SOX3; HINFP; ZNF117; ZNF225; BRDT; IRF9; TGIF1; ZNF165; SIM1; ZNF562; MDM4; BARX1; TERF1; ZNF516; HIC1; ZNF132; ZNF556; TGS1; ZNF682; MYRF; ZNF141; ZBTB3; ASCL1; FOXI1; ZNF135; KAT2B; ZNF345; TRPS1; SOX2; ZNF667; ZNF107; PAWR; PEG3; BRWD1; TEAD4; ZNF623; BNC2; MYCL; TCF21; ZNF586; ZNF331; SOHLH2; FEZF2; PKNOX1; NFATC3; EMX1; L3MBTL1; GLI2; TOPORS; ZNF544; CARF; AR; FOXJ1; MNDA; CDIP1; ING4; ZNF195; CAMTA2; KDM4C; NFE2; EHF; DLX5; ERBB4; FOXF2; FOXA2; CBFA2T3; JUN; SIX2; ZNF711; ZNF112; SKI; NANOG; DMTF1; FOXG1; KLF3; NCOA2; RBL2; CUX2; ZNF573; TCEA2; TMF1; PRDM1; ZNF415; NRBF2; HLX; MXD1; FOSL2; SPIB; NR1H2; LEF1; KLF13; HIC2; ZNF671; HOXB2; BACH1; AEBP1; SMAD7; NFATC4; ZNF239; NPAT; PITX1; ZNF12; BNC1; MECP2; WT1; SIAH2; SSBP3; NPAS2; ZNF354A; TLE4; TRIM24; MYBL1; ZNF43; MEIS1; TRIM29; ZNF329; ZSCAN18; LPIN2; ZNF426; SALL2; ZNF665; SALL1; TOX3; ZBTB16; SSBP2; NRIP1; JUP; PGR; ZNF264; NCOA1; KLF9; TCF7L2; ZNF85; PAX6; INSR; TBX2; IFI16; CREM; ZNF394; ZNF551; ZNF44; NR1D2; ZNF45; REL; BHLHE41; ZNF91; ZNF232; HLF; ZEB2; ESR1; ZNF136; ZNF267; HOXB5; HOXB6; STAT4; ZNF430