Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16622 Alpelisib GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 19 PTTG1; HLTF; RCOR1; ENO1; ASH2L; ZMYND8; MTF2; ARID4B; NUP62; SATB1; HOXA5; MBD2; ERBB2; PDLIM1; CREG1; HMGN3; KDM5D; TRIB3; BASP1
Down-regulation 63 HOXB13; JUN; LMCD1; BRD4; ZNF562; YAP1; SOX13; FOS; CNOT3; NKX2-1; HEY2; CBFA2T3; EMX2; CRYM; MYRF; ARID1A; JUNB; WDR77; HDAC4; WT1; PEG3; ZNF124; AEBP1; ERBB4; RXRA; CBX4; HDAC9; CITED2; HHEX; ZBTB16; ZNF331; MAF; INSR; NR2F1; HOXC10; HIC2; ZNF467; TCF21; NR0B1; TRPS1; SMAD6; EGR2; SSBP2; POU2AF1; THAP11; ID4; ZNF93; SALL1; SMARCA1; GLI2; MEIS1; ZNF423; BHLHE41; ZNF264; ZNF274; MNDA; ZNF43; MEF2C; HOXB6; HOXB2; ZNF91; ZNF430; IKZF1