Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16620	Alpelisib	GSE70138	MCF10A	Human	3h	10uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	ARID4B; TSC22D3; MAML1; SP3; RBPMS; NR2F1; MLXIP; HBP1; GTF2IRD1; CITED2; MYCL; SIX1; RERE; CNOT6; MED17; SMAD7; BRD4; ATF2; SOX2; CUX2; PNRC1; ID2; ZNF12; IRF9; TRIM22; ZNF268; SOX12; MNT; SATB1; STAT6; ARID1A; SOX13; HOXC4; ZKSCAN1; ZNF107; ZBTB7A; ADRB2; SMARCC2; SOX4; WNT4; MEN1; KAT6B; CHD9; CBX6; MECOM; FOXN3; FOXO3; EHF; TCF21; SIM2; RFX5; NKX2-2; TCF4; SMAD1; TULP3; HOXC10; ZNF14; MAZ; TLE2; TCF7L1; ZNF117; NR2F2; SIAH2; ZNF354A; ZSCAN31; WWC1; ELF5; SPEN; RUNX3; ZNF232; AEBP1; ZNF217; ZFPM2; HIRA; ID3; SOX11; IRF8; PAX8; HOXC6; HOXA5; PEG3; WT1; CREB1; THAP11; ZNF43; HOXD1; IFI16; BHLHE41; TRIB3; ZNF91; NR2F6
Down-regulation	69	PQBP1; CSDE1; ABT1; KLF10; HMGA1; RBBP4; JUNB; DLX2; SREBF1; ZNF721; HOXA1; CTNNB1; PSMC3; TFAP2C; NCOA6; NUP62; LIMD1; AATF; SPDEF; LOXL2; HMGA2; HAND1; LMCD1; UBE2L3; TOX; SOX9; FOSL1; EPAS1; MAFF; WDR77; ELF4; SMARCA1; HOXA11; NCOA4; FOXA2; BTF3; HIC2; PSIP1; LIN28A; POU2AF1; LITAF; ETS2; CREG1; ATF4; GTF3A; ENO1; ZFHX4; FOXC1; HNRNPD; CEBPA; BHLHE40; ZNF331; NCOA1; RAN; DLX5; SUV39H1; SMARCB1; TP63; EGR3; HDGF; VPS72; ZNF274; MSX1; IRX5; KLF9; ZBTB18; TBX2; BASP1; IKZF1