Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16619 Nvp-bez235 GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 39 TSC22D3; KAT6A; ZMYND8; SOX4; ZNF268; BARX1; PHIP; KLF6; DDIT3; ID1; MYCL; HBP1; WWTR1; SOX2; NR1H2; ZNF217; ASCL1; JUP; SOX10; TGFB1; HDAC9; ATF3; ZSCAN18; PBX3; SPEN; HMGN3; ST18; TRIM22; IFI16; NR2F6; ZFPM2; TCF4; ID3; SOX17; TOX3; HOXD1; ZNF91; TRIB3; ID4
Down-regulation 32 ZNF672; TFAM; MED1; LEF1; RNF6; NKX3-1; BRD2; PTTG1; ZMYM2; EGR3; SMARCA4; SIM2; ZNF189; TOB1; TRIP6; CEBPA; ZEB2; LPIN2; HOXA10; ID2; HOXC10; MAFB; MNDA; HOXC6; THAP11; MAF; ZBTB18; ZNF274; NCOA1; MYB; BHLHE41; IKZF1