Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16618 Nvp-bez235 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 47 TSC22D3; RAD21; TCF3; ATF2; NFIC; UBE2B; ZNF268; CDX1; ZMYND8; TAL1; JUND; RFXANK; PEX14; KDM5B; CUX2; CERS6; MEOX2; CHD9; TCF21; SOX2; TOX; JUP; WNT4; MLXIP; ZNF117; PBX3; CBFA2T3; FOXF1; HBP1; LOXL2; NFATC3; LITAF; TGFB1I1; HOXD1; DACH1; INSR; NFATC4; SATB1; NR2F6; VPS72; ST18; INSM1; TFAP2A; ZEB1; SOX17; ERBB4; TRIB3
Down-regulation 49 MAGED1; NKX3-1; NUP62; CREB1; TBPL1; MED1; TRIM32; NR2F2; SOX9; YBX3; SSX1; HIC2; ZNF266; ASCL1; CEBPG; NCOA4; XBP1; TBP; HEY1; HOXA5; BCL6; EGR3; MYCN; PIR; RNF6; ING3; ISL1; KDM5D; PCGF2; ZNF267; CEBPA; ID2; DMTF1; BAZ1A; LMCD1; ELF5; KLF4; MAF; ZNF652; HOXC10; ZNF394; ZNF443; ZBTB18; HOXC6; MAFB; IRX5; THAP11; BHLHE41; ID4