Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16617 Nvp-bez235 GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 63 TSC22D3; ELK3; UBE2B; HOXC6; BTG1; NR3C1; ZFP36L2; KLF6; GATA2; TRIM16; ITGB3BP; NFE2L1; POU4F1; ATF3; TAF10; BRD8; SREBF1; HOXB7; SMAD2; SND1; STAT6; ZMYND8; NPM1; GTF3A; MEOX2; ID1; JUNB; RBBP4; PTTG1; HBP1; BASP1; KLF2; NONO; OSR2; MED24; ARID5B; HOXA5; MYCN; RFX5; CTNNB1; MAZ; ERBB2; NR0B1; TFAP2C; AFF1; JUND; MBD2; ESR1; TXNIP; CREG1; BRD2; USP22; TRIM29; PHF20; ATF4; TLE1; MSX1; BMI1; HOXB6; HOXB2; HMG20B; HOXD1; TRIB3
Down-regulation 168 ZNF432; HMGXB4; ZNF692; MDM2; BCOR; BNC2; ZNF654; NANOG; SUPT5H; SUPT7L; ZNF573; SOX5; CBL; AR; ZNF202; CREB1; PBX3; TRRAP; ZNF180; BCL6; CENPB; SNAPC4; FUBP1; UBE3A; PKNOX2; ZNF273; ZNF562; ZBTB3; PDLIM1; ZKSCAN7; CDIP1; IRF4; PAXBP1; SIX3; TGFB1; FOXF1; SALL1; ZBTB20; ZNF124; ZNF34; EHMT2; FOSL2; ZNF235; SOX9; HIC2; ZNF331; BRD7; ZNF141; SOX3; CAMTA2; ZFHX3; SOHLH2; ZNF329; CBX4; FOXF2; HLX; KAT2B; PBX1; ELF5; SRF; CARF; ZNF75D; SPI1; MAF; DMTF1; MECP2; NR4A2; NR1H2; SMAD1; SOX2; NFATC4; ZNF12; PAX6; ERBB4; ZNF711; EGR2; BARX1; HHEX; NR2F1; IRF9; ZMIZ1; ZNF112; ZNF117; ZNF43; PITX1; MED13; IRF8; REST; ZNF227; NR1H4; ZBTB44; CBX6; TOPORS; SKI; LHX3; TCEA2; ZNF253; ZNF107; ZHX2; ZNF571; NR5A2; FOXA2; ZFPM2; NEUROD1; ZNF586; OLIG2; NFATC3; NKX2-1; TCF7L1; ZNF665; BRWD1; IL16; ZNF350; LIN28A; SALL2; ZNF175; CREB3L1; MEIS2; ZNF589; SOX11; ZNF134; TCF21; CALR; RSF1; CUX1; ZFP36L1; ZBED2; TCF4; TRIM24; NR4A1; GATA6; FOXE1; PEG3; ZNF93; ING3; ZEB2; ZNF91; PURA; REL; CHD7; FOXG1; PPARG; MYRF; ZSCAN31; TLE4; MNDA; GLI2; LEF1; EGR3; DACH1; RORA; ZNF45; TBX2; ZNF443; ZNF85; NR4A3; ZNF232; AEBP1; POU2AF1; ZNF136; TBX3; KDM5D; ZNF652; TOX3; IKZF1; BHLHE41; ID4; ZNF430