Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16615 Nvp-bez235 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 34 TSC22D3; FLNA; RBPMS; CEBPZ; SND1; CITED2; PAWR; KLF6; HLTF; HBP1; LITAF; CENPF; NR1H2; EHF; ATF3; AES; IRF7; HOXA10; ZIC1; SMAD3; TOB1; ESR1; CARM1; HOXA5; APEX1; HDGF; TLE4; ABL1; BASP1; IFI16; KLF2; TRIB3; HMG20B; ZFP36L1
Down-regulation 64 TEAD4; MED21; BHLHE41; PBX3; ZBED1; ERG; POU4F1; ZNF529; SMAD1; MEOX1; SERTAD2; BCL6; SOHLH2; ZNF556; MYBL1; THRA; ARRB1; ZNF248; NFKBIA; PHOX2B; TFEC; FLI1; MYCN; SKI; ZNF544; HIC2; SOX9; WT1; KDM5D; ZNF12; HEY1; ELF5; FOXF2; KLF11; LEF1; BACH1; ZFPM2; PAX6; PIR; ZSCAN18; VDR; FOXC1; NKX3-1; ZNF189; SSBP3; LMCD1; MEIS1; SATB1; DACH1; ZNF443; MEF2C; PEG3; MNDA; TBX2; ZEB1; GFI1; ID4; TOX3; ZNF394; ID2; ZNF267; TBX3; ERBB4; ZNF652