Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16614 Nvp-bez235 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 68 TSC22D3; KLF6; RBPMS; BHLHE40; ITGB3BP; YBX1; PSMD9; CENPF; STAT6; UBE2B; FLNA; NR4A2; RBBP4; PTTG1; DRAP1; SMARCA2; ZBTB38; NR2F2; ELF1; PMF1; HOXC6; BRD8; ZFP36L2; HMGA1; ATF3; TOB1; LITAF; YWHAB; AFF1; NPM1; MED24; HOXB7; ENO1; PUF60; ZNF281; CREG1; HMGB2; SMARCA4; USP22; HSBP1; COPS2; TAF10; HOXA5; CTNNB1; ERBB2; BASP1; NONO; SATB1; KAT6B; KLF2; SOX9; RAN; DNAJC1; TRIP6; ARID4B; PDLIM1; MEIS1; PHF20; MBD2; APEX1; KDM5D; FOSB; HOXB6; NRIP1; SCAND1; HMG20B; CRK; BMI1
Down-regulation 347 SOHLH2; ZNF345; PITX2; AR; DCC; SOX5; PAX4; ZNF234; PKNOX2; ZNF442; HEY2; PCGF3; ANKRD1; ZNF480; ZNF235; ZNF202; ZNF155; ZNF141; IKZF3; ZNF492; ZNF770; ZNF257; ZNF695; ZFP69B; ZNF675; ZKSCAN5; ZKSCAN8; ZNF208; POU2F3; BRDT; ZNF407; SCAI; SUPT7L; ZNF549; ZNF550; HOXD12; GCM2; ZNF180; ZNF682; ZNF674; ZNF80; AFF2; KLF8; ZNF225; CDX4; MED20; SOX3; ZNF124; ZBTB6; E2F8; SNAPC4; IRF4; SSX7; ZNF254; THAP9; PROX1; ZNF117; ZNF493; ZNF81; MYF5; ZNF814; ZNF415; ZBTB3; SP4; MED14; ZNF391; ZNF157; ZNF362; PRDM1; ZNF444; ZNF154; POU1F1; ZNF223; NFE2L3; ZNF613; DLX5; FOXE3; MYCL; TBX1; ZFP2; NEUROG2; POU6F2; GSC2; ZNF780B; TP53; L3MBTL1; MYBL1; SIX3; SSX1; ZNF544; SOX18; HIC2; FOXH1; THRB; BARX1; MED17; ZNF334; ZNF512B; ZNF273; POU2AF1; SIM1; FOXO1; NANOG; LZTS1; ZNF529; ZNF749; ZNF135; ZNF580; ONECUT1; SOX14; ZBTB39; ASCL2; MDM2; ZNF440; HOXD9; VENTX; KAT2B; SALL2; SHOX; ZNF22; DMRT1; PRDM9; ZNF423; ZIC3; ZNF623; IRF9; CDIP1; ZNF214; RFX1; TTF2; CDX2; MNDA; FEZF2; TAL1; NKX3-2; POU4F3; BCL6; OLIG2; ZMIZ1; HOXA3; CBX2; ZNF471; POLR3C; E2F3; LEF1; ATF5; TCEA2; TP73; ZSCAN2; ZNF236; SRY; PRDM12; LIN28A; NR1H4; ERBB4; EMX1; ZNF574; SIX6; MDM4; ZHX2; HOXA1; ZNF589; EN2; ZNF107; NR5A2; FLI1; TOX; PIAS4; CNOT3; ZBED2; ZNF12; ZNF112; CARF; CBFA2T3; ZNF146; TULP2; ZNF557; PRRX1; NFE2; ZNF74; ZNF175; NKX2-1; ZBTB44; ZNF573; TLE2; BACH2; ZNF304; HIPK2; ZNF239; ZNF586; SALL1; NR0B1; TCF7L2; NR6A1; POU4F2; NEUROD1; ZNF506; FOXA2; MED25; TFAP2C; AEBP1; KLF13; ZIM2; E2F4; CERS4; CBX4; WDR77; ZFPM2; DLX4; TCFL5; JUN; KDM5C; ZNF350; PRDM2; ZNF195; ZNF611; ZNF468; MYT1; PAWR; NFATC4; EYA1; YEATS2; TFEB; TERF1; RARG; ZNF665; EN1; NFAT5; MED13; TFCP2; ZSCAN18; CHD2; GATA6; WT1; SOX2; ELF5; ZKSCAN4; HEY1; BRWD1; SP140; ZNF671; ZNF667; CSDC2; HHEX; SSBP2; ZNF232; FOXF2; ZKSCAN7; ZNF711; ZNF701; SATB2; DLX2; SRF; NR3C2; CEBPG; ZNF211; TGIF2; ZNF248; ZNF134; TCF7L1; GFI1; TBX5; SOX10; ZSCAN16; SKI; DMTF1; CALCOCO1; ZNF516; PEG3; ZNF419; ZNF467; ZNF45; NR1H2; ID4; BACH1; SMAD7; BHLHE41; NLK; CBFA2T2; ZNF222; LMCD1; CUX2; RSF1; NKX3-1; FOXE1; ZNF354A; ZNF302; SOX11; MECP2; INSR; ST18; ZNF329; ZNF652; ZNF43; ZNF91; NFATC3; MYB; RXRA; TFEC; THAP11; ZNF264; ZNF571; PBX1; ZEB1; HOXD3; TGFB1; PBX3; EGR2; ASCL1; ZNF331; ZNF606; GLI2; ERG; ZNF426; SMAD6; ZNF85; CHD7; ZNF551; HIRA; ZKSCAN1; TCF4; RORA; CD3D; PPARG; HDAC9; MEIS2; FOXF1; RBBP8; ZNF217; TWIST1; SOX17; NCOA1; TBX2; STAT4; ID1; TLE4; ZNF394; VPS72; ZNF267; MEF2C; ID2; ZNF184; ZNF430; ESR1; CREB1; IKZF1; SNAI2