Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16604 Sb-590885 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 60 SUV39H1; VGLL4; EGR2; BATF3; WWTR1; MEF2C; HLTF; HDAC1; PIR; ELK3; RBBP4; SNW1; TSC22D3; ELF3; CBFB; MTDH; NPM1; PITX1; MNT; KDM2A; SMARCA2; NUP62; NCOR2; ELF4; CTNNB1; ASH2L; KDM5D; COPS2; NPAS2; ZBTB38; KLF5; TCERG1; ELF1; BMI1; SUB1; FOXD1; PTTG1; SFPQ; HMGB3; HNRNPD; HES1; USP22; TRIM16; FLNA; CREG1; HOXA5; GMNN; MYC; RUNX3; FOSL1; HMGN3; ZIC1; HOXB7; FOSB; CCNA2; IFI16; SATB1; HMG20B; ZFP36L1; BASP1
Down-regulation 141 NANOG; ZHX2; TCF7L2; HBP1; BTG1; EP300; TEAD3; ETS1; HEY2; SIX3; SIM1; ZNF688; DLX5; SCAI; YAP1; TSC22D1; RYBP; PBX3; MED17; ZNF154; PBX1; ING4; HDAC5; BRCA2; BCL11A; NR1H4; MYCN; CTBP2; ZBTB16; ZNF500; ZSCAN32; ZXDC; HOXC11; ZNF165; KLF13; TGIF1; PIAS1; TRPS1; SALL2; IRF9; TCF7L1; BACH1; FOS; PRDM10; JUN; BACH2; MED25; DMTF1; MXD1; CREB5; ZBTB44; PHOX2B; ZNF467; ZNF117; NFATC4; EMX2; CAMTA1; SPDEF; ZNF223; POU2AF1; FOXO4; BRWD1; ZIC3; PHIP; HIVEP1; HESX1; ZNF512B; PNRC1; ZKSCAN1; TCEA2; ZNF273; CEBPD; TULP3; SMAD1; SSBP2; VGLL1; ARID1A; MYT1L; HHEX; PEG3; NFE2L3; ZNF586; ZNF12; LIN28A; GLI2; MYB; HIC2; PRRX1; AEBP1; MYRF; ZNF93; CITED2; NR5A2; MAGED1; STAT4; CDK8; PGR; ERBB4; ARID5B; SALL1; RBBP8; THAP11; RXRA; ZSCAN18; INSR; LEF1; CD3D; GATA6; ID4; FOXE1; TLE1; ID2; MXI1; WT1; ZNF43; ZNF331; DBP; TFDP2; TOB1; MSX1; VPS72; TCF7; MEIS1; KLF11; ZNF264; RORA; NRIP1; GATA3; ZNF274; ZNF652; ZNF430; INSM1; TBX3; ZNF91; ZNF85; TBX2; BHLHE41; HOXC6; ESR1; HOXB2; MAFB