Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16594 Tg-101348 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 74 EGR1; EED; HTATIP2; MED1; UBP1; STAT6; TADA3; MED24; NCOA4; POLR3F; PITX1; PTTG1; ELF1; KAT6A; HSF2; HOXC6; RBM14; TAF10; KDM2A; BBX; TBP; BATF3; SMARCC1; NR2F2; SMARCD2; MSX1; EYA2; HLTF; ERBB2; HOXB7; CBFB; REPIN1; CTNNB1; MAX; COPS2; BAZ1A; PA2G4; HSBP1; ARID4B; EGR3; TRIP6; NEDD8; SMAD3; ABL1; SF1; PUF60; ZBTB18; FOXD1; FHL2; UBE2I; CREG1; PSIP1; MTF2; TRIM16; RUNX3; PRKDC; KMT5A; FOXJ3; YWHAB; GTF3A; RAN; MAZ; PURA; APEX1; TSC22D2; SATB2; DNAJC1; KLF2; HMG20B; IKBKAP; GMNN; HOXA5; FOSB; BMI1
Down-regulation 210 NKX2-1; SIX3; TTF2; BNC2; ARID3B; CUX2; ETS1; EPAS1; SOX3; NR2F1; HOXB13; BRIP1; ZNF480; CITED2; MED14; HOXC13; MLLT10; ZNF550; WWP1; NANOG; KLF13; ZNF141; ZNF154; EYA3; PRDM14; NR1H3; SALL2; ZNF257; BRCA2; ZKSCAN8; POU5F1B; SRY; ZNF444; POLR3C; MAML3; AR; ZNF415; YEATS4; ZFY; POU6F2; HOXC11; NFATC4; HIPK2; TBX1; ZNF440; HIF3A; SSBP2; ZIC3; TCF7L1; CDIP1; ZNF589; ZNF423; ZNF611; HNF4G; BTG1; ZNF273; RARB; EYA1; CHD2; ARRB1; EMX1; HDAC5; SOX2; ZBED2; ZNF586; FEZF2; PBX1; ZNF665; PKNOX1; LIN28A; PRDM1; ZNF33B; PEX14; CEBPD; PAX1; ZNF74; SOX18; SOHLH2; VENTX; E2F8; TULP2; MECP2; ZNF75D; ZNF682; NR5A2; ERBB4; ZNF711; HDAC9; SMAD1; RORC; MEIS2; BNC1; ELF3; MED12; KLF5; FLI1; ERG; NCOA2; HOXB1; BARX1; KLF3; DLX5; ZNF701; NFATC3; PROX1; PSMC3; PBX3; PRDM2; MAFF; HIRA; SP2; SOX13; ZNF117; TFAP2C; CSDC2; HIC2; PLAGL1; VPS72; ARL2BP; CRYM; TCEA2; PLAG1; TAF9B; VGLL1; TCF21; ZNF124; BRWD1; KDM5B; PTRF; TERF1; LHX3; HOXD11; TLE4; ARID5B; FOXG1; ZNF331; RSF1; ZNF304; TBX5; HBP1; CBFA2T2; RARG; SETDB1; ZNF573; MYRF; SOX11; DMTF1; MEOX1; ZNF350; NFE2L3; IRF9; TRPS1; TFAP2A; ATF3; ISL1; TOX; DACH1; ZNF91; ZNF467; CD3D; ID1; JUP; ZNF606; TOX3; IRF6; PAX6; ZNF571; PEG3; HHEX; SNAI2; RBFOX2; STAT3; TCF7L2; ELF5; TBX3; KLF11; POU2AF1; LITAF; TULP3; FOXE1; FOXF2; ZNF43; LPIN2; ETS2; SATB1; TCF4; MEIS1; HOXC10; GLI2; HOXD1; TBX2; NR4A3; ZNF264; ZFPM2; ASCL1; GFI1; ZNF652; ARNT2; AEBP1; ZNF85; ZKSCAN1; PAX8; GATA3; ZSCAN18; MEF2C; BHLHE41; ID4; MYB; STAT4; KDM5D