Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16593 Tg-101348 GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 46 MEF2C; ING2; ZNF84; ZNF432; ADRB2; RNF4; HLTF; TEAD1; MAX; DDIT3; ZMYND8; LOXL2; UBE2I; TRIM16; DMTF1; HDAC1; SUB1; HMGN3; RAN; THAP11; CEBPG; HTATIP2; CTBP1; LEF1; NKX3-1; NPAS2; KLF4; FOSB; PITX1; TWIST1; JUP; PTTG1; PCGF2; KLF2; BRD2; HOXA5; ZNF32; PIR; PHF20; MNDA; BMI1; BASP1; ZFP36L1; TLE1; HOXB7; MAFB
Down-regulation 84 SUZ12; JUN; MED13; BPTF; NR1H3; LITAF; EP300; TFCP2L1; BRIP1; HOXB13; MDM2; MEOX2; NEUROD2; TGS1; ZBTB16; MAFF; ZNF281; SIX3; NR0B2; RSF1; TCF15; DLX2; KDM5C; SMAD1; NFE2L3; HDAC5; NEUROG1; TRIM25; EN1; ATN1; MECP2; HMGA2; KLF13; ZIC3; ID4; OVOL1; HLX; ZHX2; KLF1; OLIG2; INSR; YEATS4; OSR2; ZMIZ1; CHD9; TCF7L1; ZBTB44; ARID5B; TRPS1; PIAS1; TULP3; SPDEF; SPEN; PBX3; CEBPD; NANOG; PAX6; ZNF131; ELF5; GATA6; ZFP36L2; CEBPA; ERBB4; EHF; INSM1; ZBTB18; ZNF423; PEG3; BCL11A; NFATC4; NEUROD1; MYB; SMARCA1; KLF9; TRIP6; ID2; PPARG; MXI1; MSX1; IRF6; RFX5; HOXB2; ZNF264; IKZF1