Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16590 Tg-101348 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 44 TSC22D3; EGR1; NR4A2; NFIL3; TOB1; TCFL5; HLTF; RCOR1; MEIS2; ATF3; NR2F1; ACTL6A; HOXA5; NFIB; ZNF423; TXNIP; TFAP2C; TBL1X; KDM5B; MYBL1; WWTR1; NR4A1; ZNF331; TGFB1; PITX1; HOXD1; ZNF217; AHR; TRIM29; LOXL2; ZEB1; HES1; TWIST1; FOSB; VPS72; HOXB6; KLF2; KLF9; TLE4; HOXB2; TLE1; NR2F6; TRIB3; ZFP36L1
Down-regulation 68 HMGA2; ADRB2; STAT6; MYC; CDC5L; TFEC; SP140L; BIRC2; JUN; FHL2; DDX17; ERG; ATF1; CEBPG; TCF12; ZBTB16; HIVEP2; NANOG; TRIM27; ZNF227; NUP62; MED1; HEY2; FOSL2; SOX4; ZNF529; ZNF248; FOSL1; LIN28A; NCOA4; AFF1; IKBKAP; ARNTL; MED24; DNMT3B; COPS2; ECD; BLM; HOXA10; SATB2; DEK; NKX3-1; CRYM; ZNF267; SUPT3H; GFI1; TLE2; GATA6; ZNF302; SMAD7; ABL1; ETS2; RFX5; GATA2; NRIP1; ARNTL2; HOXC10; ZEB2; STAT1; HOXC6; MYB; ASCL1; JARID2; MSX1; BCL11B; IRF6; ZNF430; IKZF1