Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16579 Plx-4720 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 465 KLF12; POLR2A; RERE; HLTF; CBX7; ZMIZ2; ZNF580; EP400; CTR9; HCFC1; TGFB1I1; SMARCA4; SNAPC4; RXRB; PBX2; REPIN1; MED15; NFYC; ING1; JUN; E2F2; GLI1; EP300; FOXI1; GABPB1; MED23; DAXX; ZNF212; HMGA1; AFF1; EVX1; CBX6; HOXC6; BAZ2B; BRD3; ZBTB39; ETV5; BCL3; SMARCD2; EBF2; IRF9; PAX8; ARID4A; TRRAP; SNIP1; NFKBIB; KDM5B; KMT2A; SSBP3; APBB1; KAT6A; SND1; ZNF444; SMARCD1; HCFC2; ZFHX3; ZNF646; MXD4; BRD2; NKX3-2; ZNF208; EHMT2; ZSCAN16; ARID1A; GTF2I; DDX54; ZNF226; TRIM32; TCF15; NAB2; TRIM22; ELK3; ZNF135; IRF8; ZNF304; PPARD; SLC2A4RG; KDM2A; ZNF391; ZKSCAN7; GLI2; NFKB2; MDM2; ZNF536; PCBD1; SAFB; CREBZF; STAT6; HOXC5; ESR2; SAFB2; ZBTB38; SMAD7; ZNF506; POU4F1; EYA2; TADA3; MKL1; BAZ2A; TLE2; ZNF507; ARID5A; RELA; KAT2B; BNC2; KDM5A; SOX9; TRIM16; ZBTB48; SPDEF; HDAC7; BRPF1; ZFY; LYL1; WNT4; ZNF493; CIITA; BAZ1B; PLAGL1; HHEX; ZNF140; MSL3; EN2; TSC22D4; NR2F2; POU6F1; TRIM27; BHLHE40; SCMH1; PRDM10; BHLHE41; DNAJC1; MTA2; PHF1; ZHX2; TLX2; ZNF512B; SP140; HDAC4; HOXC10; RARB; SHOX; NKX2-8; THRB; ZNF484; ZNF222; HOXC4; SMAD9; SMARCC2; MAPK8IP1; LOXL2; HABP4; AFF2; SP110; CREB3L2; HIVEP2; ZNF358; EGR1; ZBTB44; ERBB2; BRF2; MDM4; UBP1; EHMT1; GATA4; TAF1C; MYCL; CBFA2T3; POLR3F; RFX1; ZNF132; SALL1; STAT1; ZBTB20; ONECUT1; NFAT5; NR3C2; CHD3; EED; SREBF2; ZNF287; SF1; HSF2; GLI3; RSF1; TCF3; TFCP2; FOXJ1; CIC; SP3; ETV6; ZFHX2; FHL2; SIX5; FOXO4; POU2F2; KAT5; MTA1; PHF8; HSF1; TP53; ERCC3; ZNF14; SMARCA1; ZNF268; ZNF549; ATOH1; ZNF292; HLF; ZNF442; HAND2; MEN1; SMARCD3; GMEB1; WHSC1L1; ZNF225; ZBTB7C; CIZ1; GATA2; LEF1; MLLT1; JUP; ZNF814; KDM4A; ELF2; ZNF768; ZNF443; ZNF492; MYBBP1A; HIC1; MLXIP; PITX1; ZNF175; KLF15; ZBTB17; MLXIPL; MAK; ZNF556; NR5A1; TOX4; MAGED1; NR2C1; ZNF254; ZNF329; SOX3; DRAP1; ZNF112; BARX2; LZTR1; FOXN3; CREB5; ZNF671; TAF11; ZNF274; PRMT2; PEG3; E4F1; TBL1X; MZF1; CHD8; RNF10; GRIP1; DMTF1; BCL10; RBPMS; SKI; NFRKB; TCF25; ABL1; EMX1; ZNF93; NR1I3; MXD3; RING1; TSC22D2; FOXO3; FOXJ2; MED24; FHL5; ZNF835; CREB3L1; PRDM5; ZNF682; NELFB; ZNF711; SOX2; TBX3; MTF2; ZNF253; ZSCAN2; SIM2; YEATS2; ZNF667; ZNF467; VGLL4; SOX12; RBBP5; ZNF223; ZNF84; ZNF117; ZSCAN18; NHLH1; CUX1; RCOR1; ZNF695; ZSCAN32; ZNF345; MEF2C; TCF4; MAZ; FOS; IKZF1; ZNF227; ZNF180; DPF2; GATA3; FLNA; BCL6; PAX2; SIAH2; CRYM; SCAI; ZNF3; TULP1; ZNF107; CITED2; CALCOCO1; CBX4; FOXE1; USF2; VENTX; DYRK1B; SMARCC1; TRIM28; STAT5A; SHOX2; POU2F1; RUNX3; POU5F1B; POU2AF1; CIR1; HR; MSX1; NEUROD2; BCL11A; HAND1; TCF7; MGA; TRIM24; IRF5; NFIX; LIN28A; PKNOX1; ZBTB25; IRF1; ATF7IP; PNRC1; LMX1B; RRN3; EGR3; ZNF211; ZNF195; CNOT3; ZNF764; TAF6; FOXM1; ZNF184; RBL2; BRD4; ZNF813; NR1H4; TFEB; ZNF510; BTAF1; ARID5B; KLF13; ZNF528; WWTR1; AES; ZNF8; CDK8; ETV1; MAF; BRWD1; SMARCA2; TBX21; SNAI1; ZNF419; ZNF701; CRK; PCGF2; BARX1; ZNF45; EZH1; TAF10; ZNF529; NRL; IRF7; SP2; ZNF606; ZBTB7A; BBX; NCOR2; ZNF134; DLX5; SERTAD2; CSDC2; BATF; ZSCAN31; NLK; PIAS3; RORA; ZNF83; NR1D2; VDR; NFE2L3; MED1; ID2; PDLIM1; ZBTB43; CARM1; FOXJ3; BACH2; WT1; MYT1L; TLE4; ZNF415; MAFB; ZNF267; ZNF544; SOX17; HMG20B; CEBPA; PAX5; KDM5D; TBX2; GTF2F1; TAF1; ZEB2; LHX6; ESR1; NFATC1; FOSB; NKX3-1; CARHSP1; ZFPM2; FOXC1; NFATC3; MNDA; ID4; ING3; TDRD3; SMAD6; ZNF423; ZNF91; CD3D; ZNF551; PARP1; KLF2; HOXA5; ZNF43; STAT4; HOXB2; MYB; BASP1
Down-regulation 165 RHOA; PQBP1; CNBP; PEX2; PSMC3; PBX3; ID1; TEAD4; BRCA1; TAF9; ETS2; UBE2B; RNF138; TCEB2; VPS72; HDAC2; MYCBP; ILF2; COPS5; POLR3C; TFAP2A; KLF5; ATF3; TOX; SOX15; RAN; KAT2A; ATF5; NFE2L1; HMGB3; SUMO1; BRIP1; TOB1; CERS6; MYF6; TCERG1; PMF1; IRX4; TCF12; CHD7; CREG1; MED6; PSMC3IP; HEY1; NR0B1; RARA; ZMYND8; SUPT4H1; RAD21; BATF3; ENO1; THAP4; CDX2; NRIP1; TDP2; CBX3; FOXK2; PCGF1; BTF3; CSDE1; ELF4; ZNF652; ZNF410; CCNE1; CITED1; NKX2-1; RBBP8; MED27; TAF12; IRF3; CEBPD; DEK; XRCC6; DDX5; CCNC; BRD8; NR4A3; YWHAB; TTF2; SIX3; ZNF146; TGIF1; CNOT6; UBE3A; MED13; ZNF576; HDAC6; NR2F6; MYT1; ATF6; PSIP1; ID3; HMGB2; GMNN; NUP62; INSM1; ENY2; AHR; KLF7; RFXANK; ATF4; PIAS1; ZBTB16; RFC1; PCGF3; ZFP36L2; CEBPB; SSBP2; COPS2; CENPF; CTBP2; ZMIZ1; RUVBL1; UBE2I; VEZF1; RUNX1; TP63; CCNA2; TCF7L2; BRD7; MYC; SNAI2; NFYA; CREB3; IRX5; HIPK3; ARRB1; HLX; ZNF131; EZH2; JUNB; ZNF532; STAT3; SETDB1; GTF2A2; FOXF2; NKX2-2; HSBP1; PTTG1; IKBKAP; MEIS1; FOXA2; BLM; LITAF; SOX10; MYBL2; HOXD1; RREB1; MKL2; RBFOX2; ARL2BP; URI1; ELF5; CREM; PGR; ZBED2; PIR; SPEN; ARNT2; ADRB2; KLF4; PHF20; HOXB5; MXI1; TOX3