Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16577	Pf-477736	GSE70138	MCF10A	Human	3h	0.12uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	109	FOXL2; SUV39H1; ZHX2; KAT2A; FOXF2; TFAP2C; TFE3; HOXC11; E2F1; ARHGAP35; NR4A2; SIM1; TEAD1; MITF; DLX5; HLTF; PHIP; DLX4; ZNF536; SRY; CBX2; FOXI1; LZTR1; CDK2; TGIF1; PRDM10; RBPMS; SHOX; ADRB2; HOXA11; ESRRG; FOSL2; MED23; SUPT6H; OLIG2; FOXE1; MXD3; TCF3; AFF2; AES; CHD3; FLNA; KDM5D; CSDC2; TGFB1; CBFA2T3; EN1; MED25; ATOH1; ZMIZ1; BNC2; CIZ1; MECP2; FOXO4; LITAF; ELF4; CAMTA2; CNOT3; SMARCB1; MXD1; MGA; PEG3; DDX5; WWTR1; KDM5B; NR2F1; RUNX1; TFEC; NR4A1; CBX4; SOX10; TBX5; INSR; FOXN3; ATN1; PAX5; LMCD1; CHD9; RFX5; NKX2-2; MLXIP; TSC22D2; HES1; TBL1X; LHX6; POU2AF1; TCF4; PRRX1; TRIM29; FOXF1; ID2; VDR; HOXD1; ERG; HOXA10; HOXC10; TGFB1I1; NFATC3; ZIC1; ZEB1; PBX1; TBX3; ZFPM2; ABL1; FOSB; BHLHE41; SNAI2; TRIB3; ZNF91
Down-regulation	75	WHSC1; PIR; GTF2IRD1; BRD3; ZNF22; RNF4; NFYB; RBBP7; NR2F6; HDAC1; HMG20A; YBX3; PSIP1; GCFC2; TBPL1; HMGA2; ZNF410; RNF6; ZMYM2; RORA; HMGA1; RLF; SP3; RCOR3; YBX1; ALX1; CENPF; EYA1; TCEB2; RBBP4; ZNF281; CHD7; EGR3; MAGED1; COPS5; NFKBIA; EZH2; UBE2I; DACH1; SIAH2; DR1; CDK8; ELF1; MYCL; TLE1; VGLL4; KDM5A; SP110; ADNP2; ARID4B; ZFP36L2; NFIB; FOXO3; ID1; ARNTL2; SAP18; FOXJ3; ZSCAN31; GATA3; ECD; ELF5; PRKDC; GATA2; PSPC1; HMGB3; HIRA; ZNF423; CD3D; HMGB1; IKBKAP; DNMT3B; ZSCAN18; THAP11; ZNF551; MSX1