Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16576 Pf-477736 GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 45 TSC22D3; FOXL2; POU5F1B; CTBP2; SMARCD3; TRIM28; TSC22D1; MAML1; ID2; TLE4; NFKBIB; IKZF1; PRRX2; SATB1; TCF25; DNAJC2; ZNF274; HMBOX1; KDM5B; DMTF1; TRIM16; EGR3; TBL1X; SIM2; ERG; DLX5; CHD8; RBBP8; RBPJ; PSIP1; NR0B1; TOX3; STAT4; PAX8; CARHSP1; HTATIP2; NFKB2; BASP1; ZNF423; TRIM29; TRIM22; TWIST1; TRIB3; SNAI2; ID4
Down-regulation 43 HEY1; BRCA2; JUN; FHL5; PDLIM1; KAT2B; ZNF266; CAMTA1; ANKRD1; KAT6B; YAP1; BIRC2; NR1H2; ZNF587; CERS6; DEK; THAP11; MED13; ZNF529; NR3C2; COPS2; YBX3; TLE1; PAX6; ZNF175; SUB1; CREB3L2; SERTAD2; ZNF131; NR2F6; ID3; ZBTB20; CHD7; HOXA5; LEF1; ERBB4; CREG1; WT1; SCAND1; ZNF652; MYB; BMI1; ZNF91