Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16573 Pf-477736 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 65 TSC22D3; NFIL3; TCFL5; EGR1; NR4A2; GATA6; PBX3; NR4A1; CDX1; ZNF654; BHLHE40; KLF6; MAFG; MLXIP; HMBOX1; GLI3; IKZF1; NFKB1; FOSB; NFIC; CITED1; ERBB2; RELB; ID2; PNRC1; AEBP1; SOX4; KLF13; HOXA5; XBP1; RYBP; NFIB; FOXA1; HIRA; HBP1; ZMYND8; KLF7; MTF2; FOXN3; BACH2; NFKBIA; RFX5; ID3; ASCL1; INSM1; TGFB1I1; TRIM29; JUND; TOX3; STAT3; TXNIP; INSR; SATB1; ZKSCAN1; CREM; TLE4; KLF4; TCF4; FOXF1; KLF2; NR2F6; ZFPM2; HMG20B; TRIB3; ZNF91
Down-regulation 68 CREG1; VGLL4; EYA2; SMARCA2; GCFC2; EMX2; HOXA1; HEY2; ZNF692; MSX1; NR1H3; ZNF165; ZNF239; HEY1; FOXC1; HMGA1; HOXD10; HOXC4; ELF3; ZBTB38; LMCD1; SAP30; NR0B1; KAT2B; CITED2; MYC; NKX2-2; ARID4B; AFF1; TAF9B; MAF; PSIP1; HOXD11; BIRC2; MYRF; HDAC4; PDLIM1; TOX; NANOG; HOXA10; BRD2; AHR; ZNF512B; THAP11; HOXC10; ID1; CBFB; OSR2; SCAND1; MNDA; TRIP6; TP63; DLX5; TFAP2C; FOXG1; ZNF32; HOXB7; CALR; SALL1; TBX2; DNMT3B; PAX6; HOXC6; NCOA1; KDM5D; ESR1; LPIN2; SOX17