Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16567 Roscovitine GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 41 NR3C1; MMS19; MED15; TEAD1; PFDN5; TFAP2C; ZBTB38; SMARCD2; AR; NFIB; ZNF580; ELF1; GATAD2A; SOX9; TSC22D1; NPM1; XBP1; RBPMS; JUND; IRF9; PTRF; MYBL1; FOXD1; SOX10; ENO1; DMTF1; AFF1; ARID4B; HHEX; ERBB2; HOXB2; RFX5; WWC1; HIRA; FOSB; IRX5; STAT1; CRK; TRIB3; ZFP36L1; HMG20B
Down-regulation 62 MED24; POU4F1; MEOX2; UBE3A; SOX4; JUN; MECOM; NR1H3; FOXO4; TRIP4; ZNF165; TFEB; FOXN3; ZNF22; EMX2; JUNB; ZNF281; REPIN1; SMAD7; MED1; ZNF423; TERF1; TOPORS; RBL2; ZNF83; ZNF107; TAF1D; LIN28A; KLF10; ELF3; SAP18; SUPT3H; MEOX1; HLX; ING3; AEBP1; MEF2A; ERG; PEG3; MTF2; TCF21; NRBF2; CREB3L1; PBX3; KLF11; ZNF131; IRF6; TOX3; DNMT3B; MYRF; PAX5; PPARG; ZNF43; CD3D; EGR2; ZNF184; MYB; ZSCAN18; INSM1; BHLHE41; KLF2; IKZF1