Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16566 Roscovitine GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 65 KLF10; IKZF1; NCOA3; DNAJC2; RYBP; TFCP2L1; NPM1; YBX1; HLTF; NR2C1; KLF6; BCLAF1; ZBTB38; CTR9; NAB1; SMARCE1; TRIM29; FOXG1; MLXIP; CBX6; HDAC1; TOB1; FLNA; TRIM28; ZFP36L2; DDX5; BRD2; SFPQ; MAGED1; ARID4B; JUP; RAN; ESR1; HSBP1; ENO1; DMTF1; SUB1; PIR; VEZF1; SOX10; RUNX3; MITF; USP22; ARID5B; PAX5; AHR; HES1; ZIC1; LITAF; MTA1; TXNIP; CREG1; PA2G4; DNMT3B; PDLIM1; CARM1; MBD2; NKX3-1; MYC; HMGB1; ATF4; HOXA5; ID2; CCNA2; BASP1
Down-regulation 132 CCNH; PITX2; HOXB13; NFE2L3; CITED2; SOX11; PBX3; PKNOX2; EYA1; MEIS2; ZNF623; BCL10; YAP1; CERS4; NR2F1; ZNF202; HEY2; MED17; ZNF423; HINFP; LZTS1; E2F8; FOXN3; NKX3-2; RXRG; CDIP1; ZNF500; RARB; LHX2; CBX2; EPAS1; CRTC1; HBP1; ZIC3; SOX5; RXRA; ZNF112; TCEA2; ZFPM2; MYBL1; ZNF589; HOXC8; CRYM; ZNF468; ZNF350; NR3C2; L3MBTL1; ZNF175; NR5A2; HAND1; DLX4; CREBL2; TCF21; CTBP2; CALCOCO1; MXI1; BARX1; ZNF304; TCF12; RARG; ZNF573; PHOX2B; TFEC; CSDC2; THAP10; PEX14; TOX; BCL11A; PRRX1; ZBTB16; SMAD6; NFATC4; HLX; CITED1; NKX2-1; PIAS1; NR1H2; SALL2; HEY1; GLI2; IFI16; TRIB3; NRL; CARHSP1; TAF7; TWIST1; PAX6; GATA6; SERTAD2; KAT6B; PRDM2; ZEB1; DLX5; GRHL2; CEBPA; ID4; ZNF665; ZNF302; NEUROD1; MECOM; LPIN2; TCF7L2; TGFB1; NRBF2; SSBP2; MNDA; HHEX; THAP11; ERBB4; ZNF43; ZNF93; HDAC9; PBX1; MEF2C; SOX9; FOXF2; ZNF200; ID1; ZBTB18; EGR2; ST18; ZKSCAN1; ASCL1; FOXE1; MAF; PEG3; ZNF267; ZSCAN18; BHLHE41; ZNF264; ZNF184; ZNF91