Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16565 Roscovitine GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 19 CEBPZ; BATF3; BRD8; POU4F1; ASH2L; KAT6B; WWTR1; KMT5A; NR4A2; LEF1; E2F2; SUB1; TXNIP; KLF2; MSX1; ID1; KDM5D; ESR1; NR2F6
Down-regulation 77 MLLT10; ERF; RERE; MYCL; CREB3L2; BCL6; MYCN; CALCOCO1; TCF7L2; HIC2; SOX11; ZNF117; ZBED2; SIX1; ZNF665; PHOX2B; ARID1A; PBX1; ZNF652; ZIC3; GATA6; MXI1; ATF3; SALL2; ZBTB20; RXRA; NFE2; HIRA; FOXN3; MAF; LIN28A; IRF4; ARID5B; ZNF32; BLM; ZNF302; PRDM2; SUPT3H; BHLHE41; ERBB4; ZNF264; HHEX; SSBP2; TLE1; DMTF1; INSR; ZSCAN18; ZNF131; APEX1; KLF4; MEF2A; WT1; ZNF423; PAX6; ZNF91; KLF9; MEIS1; ZNF93; TDRD3; TBX3; TFDP2; SCAND1; VPS72; MNDA; DACH1; MAFB; ZNF85; ID2; TBX2; DBP; TOX3; SNAI2; SATB1; BCL11B; ZNF430; IKZF1; ID4