Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16564 Roscovitine GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 41 CREB3L2; TRPS1; CBX6; TULP4; SOHLH2; EPAS1; HAND1; ZNF415; EHF; ZMYND8; PIAS3; ZNF175; NR2F1; ARNTL; MKL2; PBX1; LITAF; PBX3; LOXL2; DLX5; SPEN; PSIP1; ZNF331; FOXF1; IRF8; SOX10; RBFOX2; SMARCA1; FOXE1; BASP1; ABL1; HOXB5; ESR1; PAX5; HOXB2; HES1; NR2F6; HOXB6; VPS72; ZFP36L1; TRIB3
Down-regulation 43 DLX2; HMGA1; JARID2; PLAGL1; CD3D; POU4F1; LEF1; ELF1; MEOX1; MAF; SIAH2; TXNIP; ERBB2; BIRC2; SOX11; MED1; CIR1; MYB; KDM5D; HOXC10; EGR3; ZBTB16; BCL11B; VDR; MEF2A; CREG1; ZNF131; PDLIM1; NFATC3; GATA6; JUP; TBX2; FOXJ3; KLF4; HOXC6; WT1; ARNTL2; ZNF267; ZNF184; BHLHE41; RFX5; SATB1; ZBTB18