Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16563	Roscovitine	GSE70138	MCF10A	Human	3h	3.33uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	77	NFE2L1; KLF10; MKL1; ZBTB38; MEIS1; HLTF; KDM2A; HSBP1; ZMYND11; RFX5; THAP11; ID1; MTF2; XRCC6; SREBF1; ISL1; STAT6; RBBP7; ID3; CTR9; GATA2; CBX5; AHR; BLM; DR1; CNOT6; PHOX2B; FOXO3; TXNIP; DDX17; YWHAB; MSX1; TOB1; CTNNB1; BATF; MTDH; MXI1; PTTG1; SMARCE1; RUNX3; SAP30; RNF141; NR4A2; ZMYND8; WT1; MLXIP; NKX2-2; SPEN; HIPK3; ID2; HOXB7; EYA2; TBX2; NR2F2; TRIP6; ELF1; MYBL1; ZNF593; BASP1; TFEC; MTA1; HES1; WWC1; MBD2; ATF4; HDGF; PAX5; FOSL1; ZBTB18; JARID2; TLE1; INSM1; NR1D2; ID4; HOXB2; ZFP36L1; MAFB
Down-regulation	190	MED17; PITX2; SUPT7L; ZNF432; SIM1; TRPS1; PAXBP1; VGLL4; HOXA7; SOX9; TRIP11; ZNF22; SIX2; PLAGL1; ARHGAP35; MAFK; ETV4; DMTF1; ZNF155; ZNF771; HMGA1; IKZF3; NKX6-1; GBX2; ZNF304; MYOD1; CNOT3; ZSCAN32; SP4; PPARGC1A; ZNF268; ZNF226; HIC1; E2F3; ZNF613; TONSL; TEAD4; SIRT2; ZNF112; MYF5; MEOX2; RAX; ZBTB32; ZFP36L2; FOXI1; HMX1; E4F1; ZNF273; YEATS4; ZSCAN5A; ZNF410; CCNH; ZNF468; NFE2L3; ZNF586; SOX18; ZBTB3; PLAG1; ZIC1; DMRT1; ZNF587; FEZF2; HR; ANKRD1; POU4F1; NPAS2; NANOG; ZNF195; ZNF74; ZNF350; GATA6; ATOH1; CUX2; AR; IRF6; FOXC1; ZHX2; ZNF682; ZNF263; CITED1; HIC2; HLX; OLIG2; YBX3; RNF138; RERE; GFI1B; RYBP; ZNF75D; FOXA1; TBX19; HNF4G; ZFX; HIPK2; HDAC5; ZNF623; RUNX1; ERG; TBX21; E2F6; CCNE1; SIX3; TBX1; KDM5C; ETV6; ZNF589; TERF1; ZNF557; TTF2; TCF7L1; ASH2L; ARID5B; NR1H4; ZNF544; GATA3; PROX1; FOXG1; CALR; NFE2; EMX1; NKX2-1; HOXA11; ZNF175; TCF7L2; HOXB1; BRD4; YBX2; SHOX2; ZFP64; TCF21; SMARCA5; TAF1D; RORA; ZNF217; E2F8; HOXD3; NPAT; MKL2; ZNF12; ADNP2; MYCL; DLX2; ZNF671; CREB3L2; USP21; CDK8; EMX2; SUPT3H; BNC1; THAP10; CBFA2T3; E2F2; IRF9; MEF2C; GTF3A; RBPJ; RNF6; JAK2; PHF20; ZNF107; FOXE1; MECOM; PSPC1; CRYM; APEX1; HIRA; SMARCA1; PDLIM1; ZEB1; ZNF443; LMCD1; VPS72; MYB; ZNF91; TCF4; ZNF45; STAT1; SCAND1; ZNF200; PPARG; HOXA5; NFKB2; ZNF267; IRF8; HOXD1; IRX5; IFI16; TBX3; SNAI2; IKZF1