Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16562 Roscovitine GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 55 SOHLH2; EGR1; PBX3; KDM5A; CDIP1; SIX6; BARX1; CUX2; FOXG1; SOX2; ZMYND8; NR4A2; IRF8; MEIS2; HEY1; CBX4; KDM5B; SNAI1; TGFB1; NR1H2; ATF3; NKX2-2; ID3; CBFA2T3; LEF1; FOXF2; POU2AF1; AEBP1; NEUROD1; ZNF331; NR5A2; ZFPM2; SPEN; NR2F1; HIC2; SOX10; MTA1; TCF21; HLX; SATB1; NFATC4; ZNF232; FOSB; ST18; KLF9; VPS72; FOXF1; NR2F6; HES1; ERBB4; TRIB3; ZSCAN18; INSM1; CREB1; SOX17
Down-regulation 44 EZH2; ATF1; ELK3; HSF2; CDK7; TBL1XR1; GABPB1; ADRB2; MED23; FHL2; ZBTB1; TAF1D; MED24; ZNF281; TRIM32; NAB1; ZMYM2; AFF1; CBFB; ZMIZ2; NR2F2; TLE1; PTTG1; IKBKAP; KAT6B; TCF7L2; ARID4B; CRYM; ERBB2; TSC22D2; ZBTB18; MAF; TOB1; NRIP1; CARHSP1; HOXC6; JARID2; RFX5; FOXJ3; MYB; BHLHE41; ZNF184; KLF2; MAFB