Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16560 Torin-2 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 165 TSC22D3; KLF12; OLIG2; BCOR; TRRAP; CNOT6; FOXL2; NCOR1; HEY1; ZMYND11; EN1; PFDN5; KAT6A; RBBP4; TRPS1; RBM39; NCOA6; CTR9; PHIP; NPM1; CTNNB1; DDX17; BARX2; CITED1; HIVEP3; FLI1; ARID4A; BACH2; TCF20; PSMD9; HOXC4; WHSC1L1; HOXA11; NAB1; CDK2; HOXA10; GATA4; TSG101; TRIM24; BAZ1B; TCF4; PKNOX2; YBX1; ZBTB40; KMT2A; SPEN; TULP4; TRIP11; JUNB; HSBP1; TRIP4; ZNF286A; VGLL4; PEG3; ATF4; KLF6; SMARCA5; MLXIP; TCF7L1; PIR; LIMD1; TRIM29; TGFB1I1; HDAC5; SMARCD3; HMGB2; UIMC1; NR4A2; TOB1; KAT6B; MAFF; BRF2; TAF12; SMAD2; THAP1; GATA3; ZBTB38; SATB1; EZH2; ZFP36L2; FOXA1; TBX3; HMGA1; SSBP3; IRF8; TP63; SOX10; TRAK1; PCGF2; ECD; ID2; ZSCAN18; CUX2; HDAC1; XBP1; ZNF516; MGA; POU2AF1; HDAC9; NCOA3; FOS; FOSB; NFKBIB; CHD7; ZNF331; AEBP1; CENPF; SOX4; RSF1; FOXO1; KDM5B; SIM2; NPAS2; INSM1; RBBP8; ATF7IP; NHLH2; ZFHX4; RFX5; MED24; HOXC10; PTTG1; BRWD1; YEATS2; NR4A1; ZNF532; HOXC6; JAK2; DMTF1; CREM; NFATC1; JUND; TLE4; ID4; SMARCA1; WWC1; SALL1; NR0B1; ZNF606; ASCL1; ZNF665; BCL11A; TOX3; OSR2; PAX8; FOXC1; ZNF329; SATB2; FOXG1; TCF7; THAP11; RLF; LMCD1; TXNIP; IRF6; ZNF274; SMARCB1; IKBKAP; CRK; MTA1; SOX17; ZIC1; ZBTB18; BHLHE41; SNAI2
Down-regulation 99 CBX3; PMS1; TEAD4; YAP1; ABT1; HDAC3; KAT2A; SIX1; TAF11; ZNF12; BCL6; PDLIM1; MED17; HMGXB4; NFE2; UBE3A; MED27; TRIP6; EED; UBE2I; MAX; CCNC; MNDA; BRIP1; KLF7; NR2F2; ZNF623; NRBF2; SP140L; TRIM27; WWTR1; TRIM33; TSC22D2; RYBP; NUP62; ATF5; TFAP2C; TRIB3; CITED2; ZNF83; PAWR; CEBPZ; IL16; PA2G4; DDIT3; ZNF468; RUNX3; TCF15; TCFL5; ETV5; RXRA; USP22; DPF2; MNAT1; ZNF22; KLF11; NFKBIA; CARHSP1; ZNF131; NFE2L3; ZNF573; CERS6; TCF7L2; SAP18; GATA2; LOXL2; RUVBL2; ZNF614; TGFB1; ZNF593; BIRC2; REST; MYT1L; TFDP2; RNF6; JARID2; RREB1; ZNF3; APEX1; CHD9; SUPT3H; MTF2; HOXA5; ARNTL2; MECOM; BCL11B; MXI1; FOSL1; HOXB7; EGR2; ZNF551; IFI16; CREG1; WT1; PHF20; CREB1; FOXJ3; ZNF184; DBP