Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16559 Torin-2 GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 133 TSC22D3; PPARGC1A; NR1H3; TFCP2L1; MED20; NFIB; HSF1; DAXX; CEBPZ; BLZF1; ZBTB16; CREBL2; NFE2L3; EBF2; ZNF623; MEOX2; EN1; SMARCA1; NR5A2; ARID3B; ZNF165; ZNF34; CREB3L2; KLF10; ASCL1; ZIC3; TFEB; NFIX; CDC5L; ZNF235; ZNF532; FOXH1; ISL1; ACTL6B; PBX1; TAF12; RNF10; ETS1; POU5F1B; ZNF536; PNRC1; FOXO1; TOPORS; ESRRG; SRY; PHIP; BNC2; FOXN3; SP140; ZMIZ1; CHD4; KDM5B; FOXO3; GATA6; DLX4; SOX4; PRDM14; KLF11; BARX1; FOXC1; TXNIP; ZNF223; LHX3; ARID3A; SOHLH2; PRDM1; KLF9; PAWR; MED13; HOXC4; SMAD3; DLX5; TCF7L1; LITAF; RBPMS; THAP10; ZNF544; SP110; CSDC2; HOXC10; GRHL2; ZEB2; IRF9; SIM2; TGIF1; ZNF573; MKL2; BACH1; TMF1; BRWD1; NR1H2; TOB1; TFEC; KLF6; SSBP3; MITF; SPIB; LHX6; TULP4; NFATC4; BLM; NR2F1; HIVEP1; PHF20; LMCD1; JAK2; INSM1; ERBB4; CARHSP1; NFATC3; ZBED2; TOX3; IRF6; NFKBIB; ZNF665; CRYM; SOX10; TULP3; CALR; BCL11A; VPS72; RBFOX2; KDM5D; ZNF426; TRIM22; PEG3; DACH1; MNDA; FOXF1; ZNF652; SNAI2; MAFB; ID4
Down-regulation 70 YBX3; LEF1; TFAP2C; CHD7; HLX; PDLIM1; EYA2; NUP62; NCOA4; CCNE1; BACH2; ITGB3BP; WT1; ZMYM2; NPM1; MED1; MTF2; CBFB; KAT6B; SCMH1; MED24; FHL2; HOXA5; TRIB3; JUND; BIRC2; BBX; SMARCC1; LOXL2; PCGF2; RFXANK; ID3; DNAJC1; NR2F6; RNF6; XBP1; TAF10; EGR2; GTF3A; EDF1; MYB; ECD; ADRB2; RUNX1; FOSL1; BMI1; ARID4B; STAT5B; SCAND1; RUNX3; ERBB2; MTDH; KLF2; ZBTB18; MYC; ZNF217; MAGED1; TRIM29; IFI16; NRIP1; POU2AF1; BAZ1A; NR4A3; ZNF148; HOXB7; RFX5; EGR3; MTA1; FOXJ3; IKZF1