Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16558 Torin-2 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 215 TSC22D3; BCL10; ZNF24; CTNNB1; UBE2B; FOXO3; ASXL1; RBPMS; BRD3; CXXC1; KAT7; TSC22D1; ZNF721; SND1; SMAD4; RBBP4; PNRC1; TOB1; YBX2; NCOA2; STAT2; CEBPZ; ZNF337; ZNF384; NCOA6; BATF; HIVEP2; HIVEP3; FUBP1; TXNIP; KDM5B; SP3; ADNP; POU5F1B; CRYM; NKRF; E2F2; BRF2; HSBP1; VGLL4; FOS; HOXC4; BTAF1; SHOX2; TRRAP; SSX1; HMGB3; BRCA1; TFEC; ZNF217; SREBF1; ZNF654; MXD4; HMGA1; TSG101; FOXD1; AIP; ZBTB38; ZBED1; ARID4B; FOXI1; ZNF266; CNOT6; TGIF2; RBL2; TAF12; NKX2-1; TRIM28; VGLL1; ELF3; CHD1; UIMC1; LYL1; ZNF160; SP140; BCLAF1; RNF14; KAT6A; SCMH1; RNF111; MAF; IKZF1; DLX4; NFX1; MLX; ZNF410; DAXX; HIPK2; RUVBL2; ASH2L; SMAD5; RNF141; ZBTB16; ECD; NFIB; ENO1; NFAT5; ZNF611; RBBP7; ID2; SMARCA1; TRIM27; LMCD1; CREB3L1; EZH1; ITGB3BP; SMAD2; TRIM22; BCL11A; STAT5A; RBM39; ARID4A; ZNF124; MED25; TRIM32; BAZ1A; TFAP2C; FOXN3; SATB1; NPM1; GLI3; REPIN1; DMTF1; ZNF528; HBP1; TCF4; PDLIM1; TGIF1; FOXG1; MYT1L; KLF7; EYA1; SMARCA2; NHLH1; FOSB; KLF9; PIR; PHOX2B; MKL2; BACH1; LHX6; STAT6; HDAC11; TBL1X; TULP4; RORC; IRX5; SETDB1; PRRX2; SFMBT1; ZNF665; CDX1; POU4F1; PLAG1; TOX3; SERTAD2; ACTL6B; HIPK3; SNAI1; SMAD7; MYB; ILF2; IRF1; LHX3; BASP1; TWIST1; ZNF248; PHF20; PCGF1; SOX2; ZSCAN9; HES1; TERF2; IRF5; EYA2; MYBL1; BLM; GFI1; NR4A1; AEBP1; HTATIP2; PRRX1; MAGED1; NFKB2; LPIN2; CASZ1; SATB2; VEZF1; CARHSP1; STAT5B; TFDP2; PAX5; PRDM2; HDAC9; RBPJ; NKX3-1; TBX2; HOXC10; TRIP6; CD3D; ASCL1; EGR3; BMI1; ZEB2; POU2AF1; CRK; NCOA1; KDM5D; ID4; TRIB3; HOXB7; ZNF652; MXI1; TLE1; HOXB2
Down-regulation 199 ZMIZ1; TAF9; CAPN15; CEBPB; ERF; SLC2A4RG; SKIL; GATA6; YAP1; HOXA7; BRCA2; BRIP1; GTF2IRD1; WWP1; RCOR1; ZFP69B; SUB1; ZBED4; ZNF202; HOXB13; ZHX2; ZNF12; C1D; NFIL3; CERS6; PMS1; MTA1; CBX3; PKNOX2; HOXA5; CBX4; BRD4; PUF60; MED13; ZNF512B; ZNF787; BCL3; E4F1; MEIS1; ARID1A; ZNF675; SOX9; THAP9; WHSC1; TGFB1; CALR; ZNF268; KAT6B; ZNF10; HEY2; BIRC2; ETV6; STAT1; RXRA; ZNF254; TEAD4; ZBTB11; MED20; HDAC1; PBX3; ZNF682; ENY2; JUNB; CERS4; YBX3; RBBP5; UBTF; ZNF165; ELF2; ZXDC; HABP4; ARHGAP35; GTF3A; TRIM29; NR1I2; CREB5; WT1; SMAD1; SP140L; ZNF140; AGO2; ZNF334; RUNX3; ZNF112; UBE3A; THAP7; ZNF257; PAXBP1; WNT4; CLOCK; IKBKAP; GFI1B; ZNF468; LOXL2; TSHZ2; SOX13; ZNF573; HMGA2; ZNF593; MEOX1; FOSL2; MNT; JUND; FOXM1; CITED1; TAF1A; ZNF84; DDX5; ZNF623; MTDH; TCFL5; RUNX1; ZNF500; TCF21; CCDC59; HOXA4; MED21; SAP18; ZNF177; ZNF571; TTF2; MYCL; TOPORS; ZNF562; CDYL; SOX18; CNOT3; ANKRD1; SOX15; ZFP36L2; CEBPG; ZNF180; THAP10; MTF2; TCF7L2; ZBTB43; PBXIP1; BHLHE41; ZNF146; TULP3; DDIT3; PROX1; PITX1; TBX3; NPAS2; TMF1; ZNF195; TLE4; PURA; SP2; CENPF; ZSCAN31; APEX1; MITF; PSIP1; PEX14; HMG20B; SMARCC2; BNC1; MNDA; SUMO1; SF1; DACH1; ZNF43; HOXD3; KMT5A; SNAI2; ATF5; AES; NR2F2; ERG; CCNC; TAL1; MEIS2; FOXF2; HNRNPD; GATA2; NR4A3; ZNF551; ID1; FOSL1; EGR2; ZNF232; HHEX; ESR1; ZFPM2; HOXA10; MSX1; SMAD6; IRF6; THAP11; LEF1; HOXD1; ZNF148; ZNF430; ZNF91; MECOM; ZNF136; ARNTL2