Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16557 Torin-2 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 72 TSC22D3; PQBP1; SREBF1; TERF1; DAXX; TXNIP; CNOT6; UBE2B; NR3C1; BRD8; CTR9; ASCL1; NR0B2; POU5F1B; NCOA2; AIP; KDM5B; ZBTB1; MAML1; BTG1; BRF2; HSBP1; CENPF; ARID4B; ELK3; NCOR2; TCEB2; ID2; ID1; IRF7; TBL1XR1; PSMC3; MED13; PTTG1; PSPC1; ELF3; LITAF; NAB1; HOXC6; BTF3; RBPMS; MLXIP; SMARCA1; SOX4; PHIP; CTNNB1; YWHAB; PURA; AEBP1; WWTR1; RBPJ; TOB1; BMI1; ATF6; ZBTB20; ZNF217; RLF; TOX3; TRPS1; ID3; POU2AF1; TCF7; HOXA5; DNMT3B; RBBP8; JUP; ESR1; CARHSP1; EGR3; HMG20B; NR2F6; MAFB
Down-regulation 99 ZNF202; FOSL2; NFRKB; NFE2; TTF2; MEOX2; TCEA1; SOX9; ZNF155; SIX3; ZBED4; ZZZ3; ZNF391; TP63; NEUROG2; CNOT3; SIX2; KLF1; GATA6; GFI1B; BRCA2; POU2F3; ZNF675; PDLIM1; NR0B1; YAP1; SOHLH2; AR; CREB5; NFATC3; ZSCAN5A; CERS4; SIAH2; ANKRD1; LOXL2; TBX1; KAT8; SERTAD2; TFAP2C; ZNF580; LMCD1; FOSL1; ZFX; NKX3-1; BHLHE40; YEATS4; SFMBT1; E2F8; CEBPG; POU4F1; CTBP1; MEIS1; MEOX1; ZNF614; TAL1; ZNF239; TLE2; ADRB2; NR2F2; RORA; BNC1; BRD4; IRF6; EYA2; MNDA; FOXE1; EMX2; IRF9; ZFP36L2; ARNTL2; MXI1; ZNF593; PGR; TLE1; NR5A2; MEIS2; ZNF226; SPEN; MAGED1; TCF4; HHEX; ZNF512B; ERBB4; LEF1; AHR; MTA1; PAX6; MEF2C; THAP11; GLI2; HES1; TRIM29; REL; WT1; ZNF136; TBX3; BHLHE41; NCOA1; ZNF430