Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16556 Torin-2 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 58 TSC22D3; CEBPA; EMX2; TFAP2C; FOXL2; ZNF282; RBPMS; PMS1; TOX; ZNF217; TWIST1; NFIC; GCFC2; SOX4; TERF1; TGIF1; OSR2; ARID5B; CNOT3; MITF; KDM5B; ZNF331; PHIP; PBX1; PIAS3; ASH2L; SUMO1; TGIF2; NR0B1; CUX2; TAF10; SSBP3; NFKBIA; ZBTB16; NKX2-2; ID2; ZNF329; LOXL2; LITAF; NFATC4; SMARCA1; STAT1; HDAC9; TULP3; TRPS1; ZNF131; FOXF2; TOB1; STAT3; TXNIP; MTA1; HOXC10; SPIB; VPS72; SOX17; CREB1; TRIB3; NR2F6
Down-regulation 74 MYC; HMGA2; ABT1; SOX9; EGR1; ADRB2; PLAGL2; ELK3; FOSL1; LEF1; SRF; FOXA1; PIR; RNF4; BIRC2; YAP1; NKX3-1; TRIM32; MAGED1; JUN; NFKB1; NUP62; IKBKAP; ELF5; EDF1; NCOA4; ZNF721; WWTR1; SMAD7; IRF1; RNF6; CERS6; DDX5; SIAH2; EGR3; PDLIM1; HOXA5; SUB1; CREB3L1; GATA6; XBP1; HLX; ADNP2; ERG; EGR2; CHD7; ZBTB38; SPEN; ZBTB18; KLF5; FOSB; ZSCAN31; MNDA; MXI1; THAP11; ETS2; FOXJ3; NRIP1; ZNF32; ZNF267; NR1D2; URI1; POU2AF1; HOXA10; CD3D; ZNF443; IRF8; MAFB; ZNF136; ZFP36L1; TOX3; RFX5; HOXB2; ID4