Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16555 Pelitinib GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 36 TSC22D3; GATA3; TCEA1; NFYB; GON4L; TXNIP; ZNF589; ZZZ3; BRD4; ATF3; SUB1; YBX1; NCOA2; ELF3; NR2F2; MAX; SP110; IRF7; TP63; ZMIZ1; ASH2L; SOX10; HOXA5; ESR1; CITED2; MITF; ARID4B; HOXC6; AEBP1; STAT1; TRIM22; HMG20B; TLE1; ZBTB18; KDM5D; BASP1
Down-regulation 97 FOSL1; FOXL2; ZNF202; EGR1; TSC22D1; MYOG; SMARCD3; MYC; BCL3; YAP1; REPIN1; TBL1XR1; GATA6; DLX2; TEAD4; HIVEP2; EYA2; ID1; SOX9; NFKB1; MNX1; BCL11A; SMAD7; ZNF224; SOHLH2; PEG3; BAZ2A; SSBP2; PRRX2; EHF; JUN; ZFHX3; HIC2; SIX2; CALR; LIN28A; ZNF574; DLX5; DDX5; NKX2-1; CEBPD; ARID1A; NFE2; FOXA2; CEBPZ; SIX1; SOX11; HHEX; TAF1D; NKX3-1; FOXF2; MNDA; CREB3L1; CUX1; FOXD1; LOXL2; CTNNB1; TAF7; ZNF512B; REL; TCF21; MAFF; NFE2L3; MYCN; ETS2; TBX3; SMAD6; ZNF652; POU2AF1; ZSCAN18; SPEN; PBX1; TCF7; PIAS1; VDR; RUNX3; ZKSCAN1; RBFOX2; TOX3; TBX2; ZNF423; THAP11; ASCL1; ZNF264; ST18; MECOM; ZNF551; ARNTL2; ZNF91; BHLHE41; SNAI2; MSX1; RFX5; ID4; SATB1; ZNF430; IKZF1