Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16554 Pelitinib GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 23 TSC22D3; RBPMS; SLC2A4RG; NFIL3; SREBF1; ATF3; EHF; DDIT3; CENPF; TOB1; TRIM29; PTTG1; GTF3A; TRIM22; JUP; ATF4; SMAD3; TRIP6; SATB1; IRF7; TRIB3; HOXB7; HMG20B
Down-regulation 66 HMGA2; FOSL1; MYC; EGR4; EGR1; HEY1; KLF10; SRF; NKX2-1; ZNF160; GTF2I; TFEC; BATF; MEOX1; HIC2; HDAC4; EPAS1; MNDA; YAP1; REST; EGR3; ARID1A; EGR2; SERTAD2; ZNF721; KAT2B; POU2AF1; CHD7; NR2F1; RRN3; ERG; TBX2; HMGB2; SATB2; WT1; SMAD7; LEF1; TOX3; GATA6; TSC22D2; ARID4B; ZNF512B; ERBB4; ZBED2; SOX11; NRIP1; ETS2; ZNF267; HOXA10; ZEB2; GFI1; ADRB2; BHLHE41; MYB; ZFPM2; TCF7; MAF; ID4; BASP1; BMI1; PEG3; ZNF43; IKZF1; ZNF652; ZNF430; BCL11B