Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16553 Pelitinib GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 51 TSC22D3; TCEA1; PPARGC1A; PITX2; HLTF; CEBPD; CNBP; CRYM; NFIL3; NFE2L1; CITED2; RBPMS; SUB1; MEOX2; PMF1; SP110; ZIC1; PTTG1; BRD8; MYT1L; SHOX2; DDIT3; HOXB7; TOX; TP63; TRIM16; HES1; PDLIM1; LOXL2; TOB1; HMGN3; HOXC10; TFDP2; IRF7; KDM5D; ATF4; HDGF; PAX6; TRIM29; IFI16; MEIS2; TXNIP; TWIST1; HOXA5; ZFP36L1; BASP1; HOXB2; TRIB3; HOXB6; HOXC6; HMG20B
Down-regulation 61 HMGA2; FOSL1; SOX9; MYC; TSC22D1; ELK3; MAFG; HIC2; SATB2; PPRC1; JUN; CHD1; FOXA2; E2F6; IKBKAP; BAZ2A; ZNF124; ETV1; TFEC; GATA6; ERG; HEY2; ZNF266; FLI1; NFE2L3; ZNF83; LEF1; HDAC1; HDAC4; ZNF12; PBX3; E2F8; DMTF1; EGR3; ZBTB43; ADRB2; NKX3-1; SMARCC2; ZSCAN18; CBFB; ZNF267; FOXG1; ZNF665; WT1; GFI1; EGR2; ZNF443; ID4; SATB1; POU2AF1; NPAT; BHLHE41; MYB; MNDA; NRIP1; PEG3; ZNF91; MEF2C; BMI1; ZNF430; TBX3