Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16552 Pelitinib GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 38 TSC22D3; NFIL3; SREBF1; HMGB3; CEBPZ; ENO1; SUB1; NFE2L1; EHF; ARID5B; TBX2; ZNF589; PITX1; TCF4; AR; XBP1; FLNA; TXNIP; RBPMS; TOB1; PIR; NR2F2; OSR2; TCF21; ERBB2; KLF9; ENY2; LITAF; PSIP1; MAGED1; HOXA5; FOXF1; CARHSP1; ESR1; RBPJ; CCNA2; TLE1; TRIB3
Down-regulation 80 HMGA2; FOSL1; MYC; NR3C1; ZNF384; HEY1; HOXA1; EYA1; NFE2L2; HIVEP2; BAZ2B; EGR1; JUN; IRF1; DLX2; MYBL1; HHEX; ELK3; MAFF; ZNF281; SATB2; TSC22D1; FOXA2; ETV5; YAP1; AHR; GCFC2; NFE2L3; ADRB2; LMCD1; CHD7; ZNF165; ELF3; NFE2; SERTAD2; HDAC9; CTNNB1; HIC2; ZNF544; CUX1; NR2F6; FOXC1; KDM5B; TCF7; HDAC4; MYRF; BACH1; URI1; WT1; DMTF1; LEF1; EGR3; BHLHE41; ZNF423; FOSB; GFI1; FOXG1; TGFB1; POU2AF1; IKBKAP; NRIP1; PDLIM1; ZNF93; STAT5B; ZNF44; TDRD3; ZNF217; KLF4; STAT4; ZSCAN18; AEBP1; MAF; EGR2; BCL11B; RFX5; ERBB4; MSX1; MYB; ZNF91; IKZF1