Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16551 Pelitinib GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 53 TSC22D3; NFATC3; PEX2; YEATS4; TOX; KLF6; RBM39; NFE2L1; RAD21; TERF1; SUB1; CNOT6; BCLAF1; BRD8; SUPT6H; MED12; PIR; GATA2; RBPMS; ATF4; EYA2; YWHAB; PMF1; PIAS3; ZFHX4; ID3; CENPF; IRF4; MTDH; NR2F1; MAZ; CRY1; CARM1; HOXD3; CREB3L1; IRF7; PDLIM1; HOXB7; ZIC1; MEIS1; SMAD6; HMGN3; ARID4B; STAT5B; KDM5D; BASP1; HOXB6; FOXF1; MECOM; WT1; ID2; MSX1; TRIB3
Down-regulation 83 HMGA2; EGR1; FOSL1; MYC; ELK3; BRD3; EGR3; HHEX; NR1H3; TGIF1; SOX9; JUNB; MYBL1; EGR4; TRIM27; EYA1; CEBPB; BBX; NFAT5; TAF1A; SP140L; CAMTA1; DDX17; ABL1; ELF1; TSC22D1; BCL6; FOXA1; NKX3-1; CREBL2; WWTR1; MAFF; CREB5; MAX; KLF10; NKX2-1; DLX2; YAP1; BRD2; NR2F6; NR4A1; LYL1; HIC2; SMARCA2; SOX4; IRF1; TFAP2C; ZBTB43; TP63; ZNF175; NFE2; IFI16; RBL2; PRRX1; BCL11A; CEBPA; HIRA; ELF5; CDK8; ADRB2; MYT1L; HOXA10; ISL1; MNDA; ZNF512B; ING3; JAK2; EGR2; ZNF274; TXNIP; FOXE1; ZNF267; ASCL1; ZNF264; KLF2; ID4; IRF6; PEG3; ZNF652; HOXC6; MXI1; TBX3; ZNF91