Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16550 Pelitinib GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 20 E2F2; SOX2; XBP1; PITX1; JUND; ZNF593; TDP2; ID3; TRIM29; ASCL1; TRPS1; ERBB2; HMGB3; ID2; ESR1; TWIST1; INSM1; NR2F6; HOXD1; TRIB3
Down-regulation 36 MYC; EGR1; HMGA2; BRCA1; RERE; ADRB2; FOSL1; ELK3; HEY1; ABL1; MAF; EGR3; KLF4; GATA6; ETS2; NR2F2; BHLHE41; BACH1; KLF9; HIC2; TXNIP; AHR; IRF8; HHEX; EGR2; LMCD1; NCOA1; POU2AF1; NRIP1; ZNF264; REL; ZNF274; THAP11; ZNF652; HOXC6; MAFB